Multiple Myeloma Genomics Portal (MMGP)
 The Multiple Myeloma Genomics Portal is a part of the Multiple Myeloma Genomics Initiative, a collaboration of The Multiple Myeloma Research Consortium, The Broad Institute of MIT and Harvard, and the Translational Genomics Research Institute (TGen). Funding is provided by the Multiple Myeloma Research Foundation. Development of the portal and data curation was performed by the portal team of the Broad Institute and Dana Farber Cancer Center.
The Multiple Myeloma Genomics Portal (MMGP) has been made available to provide access to and limited analysis of the MMGP portal data sets. These include the MMRC funded reference aCGH and gene expression data and additional public multiple myeloma datasets.
The MMGP will be updated with new features such as additional data and analysis tools as they become available.
News / Events
Apr 30, 2010: The MMGP Terms of access have been updated. Please review the revised terms of access.
more...
Apr 30, 2010: The MMGP has been updated to version 2.7.4.
Jan 16, 2010: The MMGP has been updated to version 2.3
Dec 7, 2009: Expression and copy number data for the MMRC Reference collection has been updated. It now includes 238 paired samples (from 202 previously)
Aug 12, 2009: Multimedia tutorial videos have been added for the GSEA and IGV analyses. The videos are less than 5 minutes long and are available on the HELP > DOCUMENTS page.
Jul 28, 2009: The MMGP will be unavailable from 6pm Friday July 31 through 9am Monday Aug 3rd while maintenance is performed on the Broad Institute servers.
Jun 16, 2009: The MMGP will be unavailable from midnight June 19th to midnight June 21st(EST) for server maintenance.
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New User?
Please register for full access to the data and analyses tools MMGP provides.
Terms of Access Register
Tutorials / Manuals
Tutorials, analysis descriptions and other documentation is available at:
HELP > DOCUMENTS
Publications
 Gene expression profiling of plasma cells at myeloma relapse from total therapy 2 predicts subsequent survival., Nair B et al., Blood, 2009
Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer., van Haaften G et al., Nature Genetics, 2009
A monoclonal gammopathy precedes multiple myeloma in most patients., Weiss BM et al., Blood, 2009
All Publications
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What you can do on this portal
Search for information
Enter a keyword to search for genes, news items and publications. Search
results for a gene include links to annotations and analyses.
Data Sets
 Browse, analyze and download studies and data sets.
BROWSE > DATA
Analysis Tools
 The portal provides the following analyses:
Differential Expression Analysis
Find genes that are significantly differentially expressed between two user-defined
classes of samples from an expression data set available on this portal.
Gene co-expression
View the top 20 genes in a data set that are co-expressed with a gene of interest.
Gene Set Enrichment Analysis (GSEA)
Find pathway gene sets correlated with a gene of interest. Domain experts curate the pathway
gene sets based on data from several online pathway databases.
Integrative Genomics Viewer (IGV)
Visualize a data set in the Integrative Genomics Viewer (IGV), a high-performance visualization tool for interactive exploration of
large integrated data sets.
ANALYSES
Sample Sets
Create your own sample sets based on a large number of available criteria and use them in differential expression analysis.
CREATE SAMPLE SETS
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