Gene Set: V$GATA4_Q3

Standard name V$GATA4_Q3
Systematic name M15522
Brief description Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif AGATADMAGGGA which matches annotation for GATA4: GATA binding protein 4
Full description or abstract XX
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FA GATA-4
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SY GATA-GT2.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia;
OC eutheria; rodentia; myomorpha; muridae; murinae
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CL C0003; CC (g); 2.2.1.1.4.
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SZ 440 AA; 44.6 kDa (cDNA)
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SC SwissProt #P46152 [5]
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FT 210 260 SM00401; ZnF_GATA.
FT 212 251 PF00320; GATA.
FT 216 240 zinc finger 1.
FT 264 314 SM00401; ZnF_GATA.
FT 266 305 PF00320; GATA.
FT 270 294 zinc finger 2.
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SF two different sequences published [5] [1]
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CP heart (cardiomyocytes), testis, ovary [1] [3]
CN brain, lung, liver, kidney, skeletal muscle, hypothalamus, pituitary gland,
CN adrenal gland, submaxillary gland, parotid gland [1]
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FF up-regulated in cardiomyocytes after treatment with triidothyronine or
FF retinoic acid [2]
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XX
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RN [1]; RE0009018.
RX MEDLINE; 94217709.
RA Grepin C., Dagnino L., Robitaille L., Haberstroh L., Antakly T., Nemer M.
RT A hormone-encoding gene identifies a pathway for cardiac but not skeletal
RT muscle gene transcription
RL Mol. Cell. Biol. 14:3115-3129 (1994).
RN [2]; RE0009636.
RX MEDLINE; 94277100.
RA Molkentin J. D., Kalvakolanu D. V., Markham B. E.
RT Transcription factor GATA-4 regulates cardiac muscle-specific expression of
RT the alpha-myosin heavy-chain gene
RL Mol. Cell. Biol. 14:4947-4957 (1994).
RN [3]; RE0009877.
RX MEDLINE; 95021282.
RA Ip H. S., Wilson D. B., Heikinheimo M., Tang Z., Ting C.-N., Simon M. C.,
RA Leiden J. M., Parmacek M. S.
RT The GATA-4 transcription factor transactivates the cardiac muscle-specific
RT troponin C promoter-enhancer in nonmuscle cells
RL Mol. Cell. Biol. 14:7517-7526 (1994).
RN [4]; RE0013589.
RX MEDLINE; 94240185.
RA Tamura S., Wang X. H., Maeda M., Futai M.
RT Gastric DNA-binding proteins recognize upstream sequence motifs of parietal
RT cell-specific genes. (Erratum)
RL Proc. Natl. Acad. Sci. USA 91:4609 (1994).
RN [5]; RE0013588.
RX MEDLINE; 94068504.
RA Tamura S., Wang X. H., Maeda M., Futai M.
RT Gastric DNA-binding proteins recognize upstream sequence motifs of parietal
RT cell-specific genes.
RL Proc. Natl. Acad. Sci. USA 90:10876-10880 (1993).
XX
Collection C3: motif gene sets
      TFT: transcription factor targets
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Organism Homo sapiens
Contributed by Xiaohui Xie (Broad Institute)
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