Gene Set: V$RREB1_01

Standard name V$RREB1_01
Systematic name M2610
Brief description Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif CCCCAAACMMCCCC which matches annotation for RREB1: ras responsive element binding protein 1
Full description or abstract XX
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FA RREB-1
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SY Ras-responsive element binding protein 1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia;
OC eutheria; primates
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CL C0001; CH.
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SZ 755 AA; 79.9 kDa (cDNA)
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SC translated from EMBL #U26914 and edited according to Ref. [1] in positions
SC 25, 334, 350
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FT 315 337 PF00096; zf-C2H2.
FT 315 337 SM00355; ZnF_C2H2.
FT 317 337 zinc finger 1.
FT 461 483 SM00355; ZnF_C2H2.
FT 461 483 PF00096; zf-C2H2.
FT 463 483 zinc finger 2.
FT 580 602 PF00096; zf-C2H2.
FT 580 602 SM00355; ZnF_C2H2.
FT 582 602 zinc finger 3.
FT 608 630 PF00096; zf-C2H2.
FT 608 630 SM00355; ZnF_C2H2.
FT 610 630 zinc finger 4.
FT 719 722 potential MAPK phosphorylation site.
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CP heart, kidney, liver, lung, pancreas, placenta, skeletal muscle [1]
CN adult brain [1]
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FF activator, mediates Ras- or Raf-response through Ras-responsive elements
FF (RRE) [1]
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RN [1]; RE0004978.
RX MEDLINE; 96413283.
RA Thiagalingam A., de Bustros A., Borges M., Jasti R., Compton D., Diamond
RA L., Mabry M., Ball D. W., Baylin S. B., Nelkin B. D.
RT RREB-1, a novel zinc finger protein, is involved in the differentiation
RT response to Ras in human medullary thyroid carcinomas
RL Mol. Cell. Biol. 16:5335-5345 (1996).
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Collection C3: motif gene sets
      TFT: transcription factor targets
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Organism Homo sapiens
Contributed by Xiaohui Xie (Broad Institute)
Source platform HUMAN_GENE_SYMBOL
Dataset references  
Download gene set format: grp | text | gmt | gmx | xml
Compute overlaps C1: positional gene sets
C2: curated gene sets
      CGP: chemical and genetic perturbations
      CP: canonical pathways
            CP:BIOCARTA: BioCarta gene sets
            CP:KEGG: KEGG gene sets
            CP:REACTOME: Reactome gene sets
C3: motif gene sets
      MIR: microRNA targets
      TFT: transcription factor targets
C4: computational gene sets
      CGN: cancer gene neighborhoods
      CM: cancer modules
C5: GO gene sets
      BP: GO biological process
      CC: GO cellular component
      MF: GO molecular function
Compendia expression profiles Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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