Gene Set: V$FXR_Q3

Standard name V$FXR_Q3
Systematic name M9731
Brief description Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif CARGKTSAWTRACC which matches annotation for NR1H4: nuclear receptor subfamily 1, group H, member 4
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FA FXR:RXR-alpha
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia;
OC eutheria; rodentia; myomorpha; muridae; murinae
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CL C0002; CC (rec).
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SF heterodimer, for individual polypeptides see mouse FXR-alpha and
SF RXR_alpha
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FF activator in response to bile acid induction [1];
FF regulates lipid metabolism [1];
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RN [1]; RE0018126.
RX MEDLINE; 20564299.
RA Urizar N. L., Dowhan D. H., Moore D. D.
RT The farnesoid X-activated receptor mediates bile acid activation of
RT phospholipid transfer protein gene expression.
RL J. Biol. Chem. 275:39313-39317 (2000).
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Collection C3: motif gene sets
      TFT: transcription factor targets
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Organism Homo sapiens
Contributed by Xiaohui Xie (Broad Institute)
Source platform HUMAN_GENE_SYMBOL
Dataset references  
Download gene set format: grp | text | gmt | gmx | xml
Compute overlaps C1: positional gene sets
C2: curated gene sets
      CGP: chemical and genetic perturbations
      CP: canonical pathways
            CP:BIOCARTA: BioCarta gene sets
            CP:KEGG: KEGG gene sets
            CP:REACTOME: Reactome gene sets
C3: motif gene sets
      MIR: microRNA targets
      TFT: transcription factor targets
C4: computational gene sets
      CGN: cancer gene neighborhoods
      CM: cancer modules
C5: GO gene sets
      BP: GO biological process
      CC: GO cellular component
      MF: GO molecular function
Compendia expression profiles Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 85 genes
Gene families Categorize these 85 genes by gene family
Show members (show 117 members mapped to 85 genes)
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