Tagged with #kmer
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I understand the HaplotypeCaller does some local assembly and realignment. Can someone expand on the parameters used during the local assembly? What is the kmer used for the assembly graph? I would like to explore the use of digital normalization prior to SNP calling to remove PCR artifacts and this information would be helpful.

There are 5 comments on this article. To see them or add your own, read this post on the forum