Filtering multi-sample VCFs for low DP
Posted in Ask the team | Posted on 2013-01-07 13:05:07


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Hi Team,

I have a multi-sample VCF file produced by UnifiedGenotyper. I now want to filter this file marking those variants with a low depth. However the DP entry in the info field is across all samples, and even if it were possible to assess the individual's DPs, I would then have to resolve the issue of a variant having low depth in one sample, and high in another. Any suggestions are appreciated.

Thanks for your time


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There are 16 comments on this article. To see them or add your own, view this post on the forum