Are soft clipped bases used in indel realignmment?
Posted in Ask the team | Posted on 2012-12-20 01:21:50


There are 1 comments on this article. To see them or add your own, view this post on the forum


Hi, Some aligners produce Smith-Waterman alignments and may soft clip bases from a read when there are indels or mismatches near the ends of the reads. I was wondering if you include these bases in the realignment process? And if not whether you might consider making it an option? Thanks, Colin


Return to top

There are 1 comments on this article. To see them or add your own, view this post on the forum