Combining PhaseByTransmission and ReadBackedPhasing
Posted in Ask the team | Posted on 2012-10-30 08:56:45


There are 2 comments on this article. To see them or add your own, view this post on the forum


Hello GATK Team,

there are currently two walkers for phasing in the GATK PhaseByTransmission and ReadBackedPhasing. Because of their different information source (PhaseByTransmission has the called VCF file, ReadBackedPhasing the BAM files) these can produce different or complementary genotypes. There used to be a walker for this job "MergeAndMatchHaplotypes" but it seems to be discontinued.

What is the current recommendation for Trios? Only use PhaseByTransmission?


Return to top

There are 2 comments on this article. To see them or add your own, view this post on the forum