Does HaplotypeCaller cost a lot of RAM?
Posted in Ask the GATK team | Last updated on 2012-09-19 14:48:07

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I tried to run several HaplotypeCaller jobs simultaneously on a node. But sometimes, not all the time, they caused the nodes collapse. I noticed that HaplotypeCaller sometimes occupied tens of GB of memory, is this normal? The average depth for my samples is 30x-50x.

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