Takes alleles from a variants file and breaks them up (if possible) into more basic/primitive alleles.
For now this tool modifies only multi-nucleotide polymorphisms (MNPs) and leaves SNPs, indels, and complex substitutions as is, although one day it may be extended to handle the complex substitution case. This tool will take an MNP (e.g. ACCCA -> TCCCG) and break it up into separate records for each component part (A-T and A->G). Note that this tool modifies only bi-allelic variants.
A variant set with any type of alleles.
A VCF with alleles broken into primitive types.
java -Xmx2g -jar GenomeAnalysisTK.jar \ -R ref.fasta \ -T VariantsToAllelicPrimitives \ --variant input.vcf \ -o output.vcf
These Read Filters are automatically applied to the data by the Engine before processing by VariantsToAllelicPrimitives.
This tool applies the following downsampling settings by default.
The arguments described in the entries below can be supplied to this tool to modify its behavior. For example, the -L argument directs the GATK engine restricts processing to specific genomic intervals (this is an Engine capability and is therefore available to all GATK walkers).
This table summarizes the command-line arguments that are specific to this tool. For more details on each argument, see the list further down below the table or click on an argument name to jump directly to that entry in the list.
|Argument name(s)||Default value||Summary|
|NA||Input VCF file|
|stdout||File to which variants should be written|
Arguments in this list are specific to this tool. Keep in mind that other arguments are available that are shared with other tools (e.g. command-line GATK arguments); see Inherited arguments above.
File to which variants should be written
Input VCF file
Variants from this VCF file are used by this tool as input. The file must at least contain the standard VCF header lines, but can be empty (i.e., no variants are contained in the file).
GATK version 3.0-0-g6bad1c6 built at 2014/03/06 06:38:04. GTD: NA