News / Events
Jul 23, 2014: The browse cell lines, differential expression and gene set enrichment analyses are currently off-line. We are working to restore this functionality.
Jun 6, 2014: The differential expression, GSEA and GeneNeighbors analyses are currently not working due to the recent maintenance.
Jun 3, 2014: The CCLE will be unavailable from 10AM through 1PM EST Friday June 6th for maintenance.
Nov 12, 2013: The Gene Set Enrichment Analysis (GSEA) is not currently able to run due to server issues. Engineers are working on the problem.
Sep 30, 2013: The CCLE can now upload data directly to GenomeSpace. To learn more, see the GenomeSpace blog
Sep 18, 2013: The portal will be unavailable from Thursday October 17 through Sunday October 20th for server maintenance.
Aug 6, 2013: The problems with the GeneNeighbors and Differential Expression (CMS) analyses have been corrected. All systems are functioning normally once again.
Please register for full access to the data and analyses tools CCLE provides.
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Tutorials / Manuals
Tutorials, analysis descriptions and other documentation is available at:
HELP > DOCUMENTS
Frequently Altered Genes
clouds summarizing genes frequently altered in the datasets of this
portal are available in the
Mutation tag cloud
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity, Barretina Caponigro Stransky et al., Nature 483, 603-307, 2012
Project Achilles is a systematic effort aimed at identifying and cataloging genetic vulnerabilities across hundreds of genomically characterized cancer cell lines.
The Cancer Therapeutic Response Portal provides profiles of the impact of a small-molecule collection of 185 compounds on a panel of 242 cancer cell lines
The Genotype-Tissue Expression project (GTEx) aims to create a comprehensive public atlas of gene expression and regulation across multiple human tissues