Supplementary Tables









    

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Supplementary Table 9: PTPRD somatic mutations

Genomic position (bp)Reference genotypeNormal genotypeTumor genotypeValidation Copy numberAmino acid change*SIFT Domain
8623394AAAAAG 1.72D92GDeleteriousInterPro domain: IPR013106; Pfam domain: Ig_V-set
8514867CCCCACYes2.05T229KTolerated 
8508382AAAAAGYes1.86T338AToleratedInterPro domain: IPR003961; Pfam domain: FN_III
8508187GGGGGTYes1.56G403WDeleteriousInterPro domain: IPR003961; Pfam domain: FN_III
8507943TTTTATYes1.59V484EToleratedInterPro domain: IPR003961; Smart domain: FN_III
8494333CCCCACYes1.69R585STolerated 
8475273TTTTATYes2.13L1037QDeleterious 
8450516CCCCCGYes2.16P1258RDeleterious 
8365990GGGGGTYes2.11R1537LDeleteriousInterPro domain: IPR000242; Smart domain: Tyr_PP
8321690CCCCCGYes1.92P1810RDeleteriousInterPro domain: IPR000242; pfscan: Tyr_PP


* ENST00000356435 is the transcript used for annotating the mutations.