What columns are necessary in MAF for MutSigCV?
From some of the previous posts, it sounds like the 'categ' and 'effect' columns are not necessary. If we are okay with using the new defaults (i.e. using the inputs derived from HELA cells and the cell line encyclopedia - that is MAF only), what columns are necessary / used by the algorithm? This would be helpful to me and, I think , make for more complete documentation.