• HHMI selects four Broad researchers for prestigious honor

    Haley Bridger, May 9th, 2013

    The Howard Hughes Medical Institute (HHMI) announced today that four scientists from the Broad Institute are among the 27 “top biomedical researchers” in the nation who will become HHMI investigators this fall. Selected for their scientific excellence, all of the investigators will receive flexible, financial support over the next five years so that they may move their research forward in creative and new directions. The Broad Institute’s Aviv Regev, Vamsi Mootha, Peter Reddien, and David Reich are among the new group of HHMI investigators.

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  • A need for speed

    Haley Bridger, May 6th, 2013

    A patient’s genetic sample holds great promise – but to capitalize on it, researchers need to crack open the information within, analyze it, and return the data to doctors in time to influence critical healthcare decisions. Broad Institute researcher Chris Friedrich and his team are challenging themselves to find ways to deliver information faster than ever before, efforts that in the future could help patients.

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  • Inflammatory finding

    Paul Goldsmith, May 2nd, 2013

    To convert food into energy, our bodies rely on a complex network of molecular pathways known broadly as metabolism. Along the path from food to energy, intermediate molecules emerge that form the starting materials for the next step. Traditionally, these intermediates were viewed simply as building blocks — essential for the process, but otherwise inert.

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  • Creature Feature: African eye worm (Loa loa)

    Leah Eisenstadt, April 25th, 2013 | Filed under

    The human microbiome project revealed the vast numbers and types of microbes that live on and in the human body. While this thought may be unpleasant, humans can have larger, more gruesome passengers hitching a ride, such as the several-centimeter-long nematode Loa loa, which infects millions of people in Western and Central Africa.

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  • David Altshuler elected to the American Academy of Arts and Sciences

    Leah Eisenstadt, April 24th, 2013

    Join us in congratulating David Altshuler, chief academic officer and deputy director of the Broad Institute, on his election to the American Academy of Arts and Sciences. As a member, he joins some of the world’s most accomplished leaders from academia, business, public affairs, the humanities, and the arts, including Broad director Eric Lander and institute founder Eli Broad.

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  • "Coelacanth Chat" coming soon

    Haley Bridger, April 23rd, 2013

    Last week, we shared exciting news about the sequencing of the coelacanth genome with you in a Broad press release and video. If you want to learn more about coelacanths, join us online this Thursday, April 24, at 11 a.m. EST.  Watch live as science writer Carl Zimmer and scientists from the team that sequenced this remarkable fish’s genome explore the stories behind the science, discuss the latest discoveries, and answer your questions in a Google Plus Hangout On Air.

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  • Meet a Broad physician-scientist: Adam Bass

    Veronica Meade-Kelly, March 29th, 2013 | Filed under

    Perhaps no one has a more complete picture of a disease than a physician-scientist does. Take Adam Bass, who this week published, with his co-authors, a study on the genome sequence of esophageal adenocarcinoma (EAC), a deadly cancer that starts in the lower esophagus: as a physician, Bass has cared for patients afflicted with EAC, and has seen its devastating effects. As a research scientist, Bass has also seen the inner workings of the disease, and is hunting for its vulnerabilities.

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  • Rewinding the clock with epigenomics

    Haley Bridger, March 28th, 2013

    How does a single cell give rise to a fully formed organism? Insights from induced pluripotent stem (iPS) cells – cells whose developmental clocks have been wound backward to an earlier time – have helped scientists develop a deeper understanding of this process. Since scientists discovered how to create iPS cells seven years ago, researchers have begun to see parallels between the steps required to make iPS cells in the dish and the molecular events that unleash a cancer cell.

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  • Fine needlework

    Veronica Meade-Kelly, March 7th, 2013

    Prick your finger with a pin, and you’re likely to have a reflexive response – possibly blood, a jerk of the hand, and an anguished cry. Penetrate the skin with a finer tool, however, such as an acupuncture needle or a mosquito’s proboscis, and the reaction – if there is one – might not be as immediate or severe; the piercing invader is simply too slight to notice.

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  • Charted islands

    Consider the classic "message in a bottle" scenario: a man is stranded on an uncharted landmass far from civilization. Thanks to his watertight missive, he is able to let others know that he's out there — that the landmass on which he is marooned exists somewhere in the world. However, without any reference points, his exact location remains a mystery.

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