Blog

  • Venturing into noncoding RNA

    Leah Eisenstadt, August 29th, 2011

    The central dogma of molecular biology states that DNA makes RNA, which makes protein, the functional players in the cell. But like most rules, this one has some exceptions.

    0 Comments
    Read More
  • Meet a Broad physician-scientist: Benjamin Ebert

    Alice McCarthy, August 18th, 2011

    Ben Ebert is as fluent in the care of patients with blood disorders as he is applying the latest genomic technologies in his laboratory at the Brigham and Women’s Hospital and with colleagues in the Broad’s Cancer Program. It’s all part of the same mission for Ben—to understand blood disorders and cancers at the genetic level to find ways to end the suffering of people with these illnesses.

    0 Comments
    Read More
  • Video: Journey of a cancer sample, part 4

    Haley Bridger, August 17th, 2011

    Every drop of DNA derived from a patient’s tumor is precious.

    Mark Puppo and Kristin Anderka are highly aware of how much time and effort has been devoted to each of the samples they are examining today. As you will see in the video below, they take great care in handling each sample and all of the chemicals in their section of the laboratory.

    2 Comments
    Read More
  • Fishing with a screen

    Elizabeth Cooney, August 15th, 2011 | Filed under

    Robots and the fleet of professional scientists who make sure the machines do their job in high-throughput screening may seem far afield from a fishing expedition. But that may be the best metaphor to explain how researchers at the Broad and elsewhere trawl for chemical compounds that might lead them to a new understanding of human biology.

    0 Comments
    Read More
  • From summer students to full-time scientists

    Elizabeth Cooney, August 15th, 2011

    Each summer talented undergraduates enrolled in the Broad Diversity Initiative’s Summer Research Program in Genomics (SRPG) fan out among the institute’s labs, performing research, attending seminars, and soaking up science before returning to college in the fall.

    0 Comments
    Read More
  • Five questions for Martin Leach

    Haley Bridger, August 12th, 2011 | Filed under

    At the Broad, collaboration is king. But in order to share ideas and data, scientists need a robust infrastructure that can support the volume and speed at which results are produced. That’s where Chief Information Officer Martin Leach and his team of experts in information technology and research computing come in. Their goal is to provide the software and technology that will enable the best collaboration experience, which will in turn accelerate groundbreaking science to transform medicine.

    3 Comments
    Read More
  • Behind the scenes of The Cancer Genome Atlas: part 2

    Leah Eisenstadt, August 11th, 2011 | Filed under

    Yesterday on the blog, we introduced you to some of the Broad researchers who built tools, teams, and resources to generate and analyze a massive flood of data and analytical code for The Cancer Genome Atlas (TCGA). Today we give you a look at the system they built to manage data analysis for the project: Firehose.

    0 Comments
    Read More
  • Behind the scenes of The Cancer Genome Atlas: part 1

    Leah Eisenstadt, August 10th, 2011 | Filed under

    In this two-part series, we’ll give you a look at some of the tools, teams, and resources built by Broad Institute scientists to support the large-scale cancer sequencing project known as The Cancer Genome Atlas (TCGA).

    0 Comments
    Read More
  • Highlights from the 2010 Annual Report: Aviv Regev focuses on how cells are “wired”

    Leah Eisenstadt, August 3rd, 2011 | Filed under

    Cells use a complex network of connections to make a constant array of decisions about their surrounding environment: Is it time to grow? Is it time to change into a different type of cell? When a cellular component or connection is missing or defective, disease takes hold.

    1 Comments
    Read More
  • Biology visualization workshop videos now online

    Leah Eisenstadt, July 29th, 2011 | Filed under

    This spring, artists, designers, computational biologists, and software engineers gathered in the Broad Institute auditorium for three days of talks, posters, and tutorials on the cutting-edge field of visualization in biology.

    0 Comments
    Read More