• CellProfiler’s identifying features

    Veronica Meade-Kelly, July 22nd, 2013

    It’s one of the great quandaries of the Information Age: as advances in digital technologies allow us to generate data at an ever-increasing pace, there is a concomitant need to find new ways to process and analyze the resulting deluge of information.

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  • Sneak preview of “Unweaving the circuitry of human disease”

    Veronica Meade-Kelly, July 19th, 2013

    Midsummer Nights’ Science continues next week with the “Unweaving the circuitry of human disease,” the third lecture in this year’s series. Broad associate member Manolis Kellis will be speaking at the July 24 event, discussing current efforts to build high-resolution activity maps of gene and regulatory regions across hundreds of cell types. These maps are bringing the genome to life, revealing possible culprits in human disease, and exposing the circuitry likely responsible when the genome’s regulatory system goes wrong.

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  • Sneak preview of “Exploring the genome’s ‘dark matter’”

    Paul Goldsmith, July 12th, 2013

    Update July 18: Check out a Storify of the live tweets from this event.

    In the second 2013 installment of Midsummer Night’s Science, our annual public lecture series, medical oncologist and Broad associate member Levi Garraway will explore how genomic technology is helping to reveal cancer’s long-held secrets, and the many ways those findings, both the expected and unexpected, are changing the lives of patients.

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  • Sneak preview of “The road to vital therapy”

    Haley Bridger, July 5th, 2013

    Midsummer Nights’ Science has become an annual tradition at the Broad Institute, and this year our first lecture in the series offers something extra special: a panel discussion featuring several luminaries from the world of chemical biology and drug discovery. This is the first panel discussion in the history of the series and promises to be a thought-provoking conversation about drug discovery and how we might mitigate suffering from disease in the future.

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  • Five Questions for Dawn Thompson

    Veronica Meade-Kelly, June 21st, 2013 | Filed under

    Dawn Thompson has spent much of her career studying yeast. The experimental biologist, who is assistant director of the Broad’s Cell Circuits Program, and group leader in core member Aviv Regev’s lab says that she fell into the field “by accident.” While interviewing for her first post-college research position, she happened to hit it off with a yeast geneticist. After working in that lab, she went on to graduate school.

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  • White House selects David Altshuler as “Champion of Change”

    Haley Bridger, June 20th, 2013

    Today, the White House will honor David Altshuler, on behalf of the global alliance for sharing genomic and clinical data, as an Open Science Champion of Change. The White House selected Altshuler for his “tremendous work and leadership” as part of this global alliance to develop a common framework for sharing scientific data.

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  • Precocious puberty gene found

    Veronica Meade-Kelly, June 18th, 2013

    The storybook character Peter Pan may have escaped the fate, but in the real world growing up is inevitable. Biologically speaking, the turn to adulthood happens in humans when the brain tells the pituitary glands to start producing hormones, jump-starting puberty. This typically happens around age 10 in girls and 11 in boys. But, for a small percentage of children, the process can start much earlier. If the brain initiates the process before age 8 in girls or 9 in boys, the child experiences central precocious (or “early”) puberty.

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  • Gaining ground on glioblastoma

    Paul Goldsmith, May 30th, 2013

    Researchers in the Broad’s Epigenomics Program recently identified a key mechanism in glioblastoma, the most common and aggressive form of brain tumor. In a study published last week in Cell Reports, the team, which includes program director Brad Bernstein, revealed that certain regulatory proteins play a major role in the “self-renewing” cancer stem cells that drive glioblastoma growth.

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  • ATARiS hits the jackpot

    Haley Bridger, May 21st, 2013

    Listening to data isn’t easy. Massive amounts of data are often messy and complicated. But somewhere within the cacophony, information can harmonize and produce the sweet sound of discovery – if you have the right tools with which to hear it.

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  • Meet a physician-scientist: Rameen Beroukhim

    Veronica Meade-Kelly, May 17th, 2013 | Filed under

    Rameen Beroukhim realized early in his medical training that he wanted to be an oncologist.

    “In medical school, I had the opportunity to work with patients who had cancer,” he explains. “I was struck by how vibrant – and how essentially healthy – many of these patients were, despite the fact that they were contending with such a challenging disease.”

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