Blog

  • Single driver mutation found in rare brain tumor

    Leah Eisenstadt, January 30th, 2014

    For patients with a rare brain tumor known as craniopharyngioma, the treatment options are slim — and often hazardous. Although the tumor is usually not aggressive, its location is perilous. Growing at the base of the skull near the pituitary gland, the tumor compresses parts of the brain as it enlarges, causing vision and learning problems and endocrine dysfunction, as well as morbid obesity. There is currently no drug to shrink the tumor, so the only options are surgical removal and radiation, which can leave patients with serious, lasting problems.

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  • Ancestral legacy

    Veronica Meade-Kelly, January 29th, 2014

    It’s part of human nature: we look at ourselves in the mirror and see links to the past. “Those bright green eyes?” we think. “Those came from grandma.” “The cleft chin? That’s from dad’s side.” Our instinct, of course, is to attribute notable traits to close relatives – those that we know personally or through family history. The reality, however, is that the genetics that influence our traits – or “phenotypes” – could date back generations.

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  • Broadies named to ‘30 under 30’

    Paul Goldsmith, January 10th, 2014

    The annual Forbes ’30 under 30’ was revealed this week, and two members of the Broad community, Cigall Kadoch and Aleksander Kostic, were named to the list. Now in its third year, ’30 under 30’ recognizes the brightest young talents in 15 different fields, including science and healthcare, technology and finance.

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  • Charting the RNA epigenome

    Leah Eisenstadt, December 13th, 2013

    In science, sometimes you need to dive deep to see the big picture. Scientists at the Broad Institute have demonstrated this time and again, enabling biological discoveries by generating dense maps, such as the survey of thousands of epigenetic marks on DNA across the human genome conducted as part of the ENCODE project.

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  • The drug works…but why?

    Veronica Meade-Kelly, December 11th, 2013

    What: A team led by Broad scientists has uncovered how the cancer drug lenalidomide works. Lenalidomide has been used for nearly a decade to treat multiple myeloma and other disorders that affect blood cells found in bone marrow, but its exact mechanism of action hadn’t previously been understood.

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  • Holiday closing from Dec. 23, 2013 to Jan. 1, 2014

    Haley Bridger, December 6th, 2013

    To give employees ample time to celebrate the holidays with friends and family, the Broad Institute will close from Monday, December 23, 2013 to Wednesday, January 1, 2014. It will reopen on Thursday, January 2, 2014.

    Our websites, of course, will still be up and running during the closing, allowing researchers all over the globe to continue accessing data, software, tools, and more.

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  • Broad announces new Merkin Institute Fellows

    Paul Goldsmith, November 22nd, 2013

    The Broad Institute is pleased to announce the latest class of Merkin Institute Fellows. The Broad’s first endowed fellowship, the Merkin Institute Fellows program was established in 2012 by Dr. Richard Merkin to provides sustained support for some of the most promising and ambitious scientists pursuing bold research at the Broad. The 2013-2014 recipients represent three of the Broad’s fastest rising stars: Sangeeta Bhatia, John Doench, and Angela Koehler.

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  • Broad stays at the top

    Veronica Meade-Kelly, November 19th, 2013

    The Boston Globe has once again listed the Broad Institute among the “Top Places to Work” in Massachusetts. It is the fourth year in a row that the institute, which prides itself on its interdisciplinary community and collaborative spirit, has earned the honor, which recognizes workplace satisfaction.

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  • A new phase for the microbiome

    Leah Eisenstadt, November 6th, 2013

    For the last five years, scientists at the Broad Institute have been helping generate a catalog of the trillions of microorganisms living on – and in – the human body. We now know that these passengers, collectively known as the microbiome, are not merely cargo; they have physiologic effects, both positive and detrimental, on their human hosts.

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  • Insights into OCD and Tourette syndrome

    Haley Bridger, October 28th, 2013

    What: Researchers are beginning to probe the underlying genetic basis of obsessive compulsive disorder (OCD) and Tourette syndrome (TS), two neuropsychiatric disorders that frequently co-occur in families.

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