• Five Questions for Dawn Thompson

    Veronica Meade-Kelly, June 21st, 2013 | Filed under

    Dawn Thompson has spent much of her career studying yeast. The experimental biologist, who is assistant director of the Broad’s Cell Circuits Program, and group leader in core member Aviv Regev’s lab says that she fell into the field “by accident.” While interviewing for her first post-college research position, she happened to hit it off with a yeast geneticist. After working in that lab, she went on to graduate school.

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  • White House selects David Altshuler as “Champion of Change”

    Haley Bridger, June 20th, 2013

    Today, the White House will honor David Altshuler, on behalf of the global alliance for sharing genomic and clinical data, as an Open Science Champion of Change. The White House selected Altshuler for his “tremendous work and leadership” as part of this global alliance to develop a common framework for sharing scientific data.

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  • Precocious puberty gene found

    Veronica Meade-Kelly, June 18th, 2013

    The storybook character Peter Pan may have escaped the fate, but in the real world growing up is inevitable. Biologically speaking, the turn to adulthood happens in humans when the brain tells the pituitary glands to start producing hormones, jump-starting puberty. This typically happens around age 10 in girls and 11 in boys. But, for a small percentage of children, the process can start much earlier. If the brain initiates the process before age 8 in girls or 9 in boys, the child experiences central precocious (or “early”) puberty.

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  • Gaining ground on glioblastoma

    Paul Goldsmith, May 30th, 2013

    Researchers in the Broad’s Epigenomics Program recently identified a key mechanism in glioblastoma, the most common and aggressive form of brain tumor. In a study published last week in Cell Reports, the team, which includes program director Brad Bernstein, revealed that certain regulatory proteins play a major role in the “self-renewing” cancer stem cells that drive glioblastoma growth.

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  • ATARiS hits the jackpot

    Haley Bridger, May 21st, 2013

    Listening to data isn’t easy. Massive amounts of data are often messy and complicated. But somewhere within the cacophony, information can harmonize and produce the sweet sound of discovery – if you have the right tools with which to hear it.

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  • Meet a physician-scientist: Rameen Beroukhim

    Veronica Meade-Kelly, May 17th, 2013 | Filed under

    Rameen Beroukhim realized early in his medical training that he wanted to be an oncologist.

    “In medical school, I had the opportunity to work with patients who had cancer,” he explains. “I was struck by how vibrant – and how essentially healthy – many of these patients were, despite the fact that they were contending with such a challenging disease.”

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  • Cellular archeology

    Paul Goldsmith, May 15th, 2013

    Imagine you’re visiting the Acropolis. You tour the ruins, taking snapshots as you go. Later, at home, you tell your family and friends about your visit and someone, noticing the building’s advanced deterioration, asks: well, how did it get that way? Now, say you knew nothing about the Acropolis, and could only rely on your photos and memory to describe the place. What would you say? Without the rich archeological history of the Acropolis, you’d be missing a huge part of the story.

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  • Predisposed to statistical genetics

    Veronica Meade-Kelly, May 13th, 2013

    You could say it’s in his genes: when it comes to his professional proclivities, Ben Neale takes after his parents.

    The trio share an interest in statistical analysis and behavioral research: Neale, an associated researcher at in the Broad Institute’s Stanley Center for Psychiatric Research and the Broad’s Program in Medical and Population Genetics, is a statistical geneticist who studies neurological disorders such as autism, attention deficit hyperactivity disorder (ADHD), and schizophrenia.

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  • HHMI selects four Broad researchers for prestigious honor

    Haley Bridger, May 9th, 2013

    The Howard Hughes Medical Institute (HHMI) announced today that four scientists from the Broad Institute are among the 27 “top biomedical researchers” in the nation who will become HHMI investigators this fall. Selected for their scientific excellence, all of the investigators will receive flexible, financial support over the next five years so that they may move their research forward in creative and new directions. The Broad Institute’s Aviv Regev, Vamsi Mootha, Peter Reddien, and David Reich are among the new group of HHMI investigators.

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  • A need for speed

    Haley Bridger, May 6th, 2013

    A patient’s genetic sample holds great promise – but to capitalize on it, researchers need to crack open the information within, analyze it, and return the data to doctors in time to influence critical healthcare decisions. Broad Institute researcher Chris Friedrich and his team are challenging themselves to find ways to deliver information faster than ever before, efforts that in the future could help patients.

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