Blog

  • Five (more) questions for David Root

    Veronica Meade-Kelly, June 12th, 2015

    Four years ago, David Root talked with us about the fundamentals of RNA interference (RNAi) technology. But, since then, the group that Root oversees – Broad’s erstwhile RNAi Platform – has taken on a new identity: it’s now known as the Genetic Perturbation Platform (GPP).

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  • GTEx: Useful expression for cancer research

    Veronica Meade-Kelly, May 20th, 2015

    This month, the Genotype-Tissue Expression (GTEx) Project, which set out five years ago to create a comprehensive atlas and open database of gene expression and gene regulation across human tissues, published several papers reporting on findings from its two-year pilot phase.

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  • Five Questions for Kristin Ardlie

    Veronica Meade-Kelly, May 7th, 2015

    The Genotype-Tissue Expression (GTEx) project started five years ago with the goal of creating a comprehensive atlas and open database of gene expression and gene regulation across human tissues. This week, the researchers spearheading the NIH-funded effort released five papers reporting on the pilot phase of the project.

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  • Broad Summer Scholar wins prestigious Intel science prize

    Veronica Meade-Kelly, March 27th, 2015

    Each year, well over a thousand promising high school science students enter the Intel Science Talent Search, long considered the nation’s most prestigious science competition. When all is said and done, only three take home top honors and the accompanying $150,000 prize.

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  • Epigenomics roadmap: where the road has led

    Veronica Meade-Kelly, February 20th, 2015

    The completion of the human reference genome over a decade ago served as a springboard for countless studies of genetic variation and its role in disease, but understanding how the body operates at the DNA sequence-level isn’t enough to resolve some of the finer points of human biology. Specifically: how can the same sequence of genetic code give rise to over 200 different cell types that perform distinct biological functions? And how might the processes that give rise to that functional variation contribute to human disease?

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  • Introducing: B60

    Veronica Meade-Kelly, November 25th, 2014

    B60, a new video series appearing on the Broad Institute YouTube channel, is a window into Broad science and culture. Each 60-second video offers a glimpse into the innovative work taking place at the institute, and the spirit of collaboration and creativity that makes it possible. Watch the series to learn how the Broad is tackling some of the most ambitious challenges in biomedicine today.

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  • Cancer gene found hiding in plain sight

    Veronica Meade-Kelly, October 27th, 2014

    A mutation that may be driving as many as 20 percent of endometrial and colorectal cancers has come to light this week, thanks to a study by researchers from the Broad Institute of MIT and Harvard and Dana-Farber Cancer Institute.

    The researchers describe finding the connection between the gene RNF43 and these cancers earlier this week in Nature Genetics.

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  • Sangeeta Bhatia awarded Lemelson-MIT Prize

    Veronica Meade-Kelly, September 8th, 2014

    Broad senior associate member Sangeeta Bhatia has been named the 2014 recipient of the $500,000 Lemelson-MIT Prize. The honor, which is celebrating its 20th year, recognizes outstanding, mid-career inventors who are improving the world through technological invention, and demonstrating a commitment to mentorship in science, technology, engineering, and mathematics.

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  • Finding the mutations that matter

    Veronica Meade-Kelly, August 7th, 2014

    A major endeavor in genomics research, at the Broad Institute and beyond, is to identify the variations in the human genetic code that may be associated with disease. Such variations can point to potential drug targets or shed light on the biological mechanisms underlying a disease.

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  • In the news: WBUR talks with Broad scientists on “Brain Matters”

    Veronica Meade-Kelly, June 20th, 2014 | Filed under

    Steve Hyman, director of the Broad Institute’s Stanley Center for Psychiatric Research, was recently featured in WBUR’s special series “Brain Matters.” The series, which will run through July 24, aims to report “from the front lines of neuroscience,” and is exploring issues and trends in neurological and psychiatric research.

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