Blog

  • Studies converge on ALS

    Veronica Meade-Kelly, April 4th, 2014

    What: Researchers from the Broad Institute, the Harvard Stem Cell Institute (HSCI), and Boston Children’s Hospital (BCH) used an eclectic combination of cutting-edge technologies to determine what’s going wrong at the molecular level in the neurodegenerative disease amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. Their research, published online this week in two separate Cell journals, sheds light on the mechanisms that lead to the disease and highlights potential targets for new treatments.

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  • Setting the standard in proteomics

    Veronica Meade-Kelly, February 27th, 2014

    What: Members of the Broad’s Proteomics Platform were the lead authors of a recent paper that outlined best practices for developing and publishing studies involving one of the field’s signature tools: targeted mass spectrometry (MS).

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  • Ancestral legacy

    Veronica Meade-Kelly, January 29th, 2014

    It’s part of human nature: we look at ourselves in the mirror and see links to the past. “Those bright green eyes?” we think. “Those came from grandma.” “The cleft chin? That’s from dad’s side.” Our instinct, of course, is to attribute notable traits to close relatives – those that we know personally or through family history. The reality, however, is that the genetics that influence our traits – or “phenotypes” – could date back generations.

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  • The drug works…but why?

    Veronica Meade-Kelly, December 11th, 2013

    What: A team led by Broad scientists has uncovered how the cancer drug lenalidomide works. Lenalidomide has been used for nearly a decade to treat multiple myeloma and other disorders that affect blood cells found in bone marrow, but its exact mechanism of action hadn’t previously been understood.

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  • Broad stays at the top

    Veronica Meade-Kelly, November 19th, 2013

    The Boston Globe has once again listed the Broad Institute among the “Top Places to Work” in Massachusetts. It is the fourth year in a row that the institute, which prides itself on its interdisciplinary community and collaborative spirit, has earned the honor, which recognizes workplace satisfaction.

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  • Levi Garraway awarded Paul Marks Prize for Cancer Research

    Veronica Meade-Kelly, September 26th, 2013

    Broad senior associate member Levi Garraway is one of three young investigators to receive this year’s Paul Marks Prize for Cancer Research. The award is bestowed every other year by Memorial Sloan-Kettering Cancer Center to promising scientists under the age of 45 in recognition of their contributions to cancer research.

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  • Five Questions for Feng Zhang

    Veronica Meade-Kelly, September 17th, 2013 | Filed under

    Core faculty member Feng Zhang, who joined the Broad in 2011, has quickly earned a reputation as one of the brightest young scientists working today. His research on optogenetics and genome engineering earned him a spot in this year’s “Brilliant 10,” Popular Science magazine's annual list of the most promising scientific innovators.

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  • New regulatory terrain

    Veronica Meade-Kelly, August 28th, 2013

    When readers get their hands on the print edition of their favorite scientific journal, they might not realize that the eye-catching graphic on the cover may have been conceived by some of the authors inside its pages. Many notable journals invite researchers to submit cover proposals when they notify them that their paper has been accepted for publication in an upcoming issue.

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  • Exploring India’s genetic history

    Veronica Meade-Kelly, August 19th, 2013

    What: Following up on a 2009 study that traced the genetic heritage of nearly all modern Indian groups to two distinct ancestral populations, Broad researchers and their Indian colleagues analyzed genomic data from across present-day India and found that most of India’s population mixture occurred 1,900 to 4,200 years ago.

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  • Algorithm seeks meaningful relationships

    Veronica Meade-Kelly, August 2nd, 2013

    Networks are ubiquitous these days: we use the internet to surf through a seemingly endless network of linked sites; we rely on social media to network with friends and acquaintances across the globe; and we’ve come to look at the human body as an interconnected system of biological processes.

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