Blog

  • Gaining ground on glioblastoma

    Paul Goldsmith, May 30th, 2013

    Researchers in the Broad’s Epigenomics Program recently identified a key mechanism in glioblastoma, the most common and aggressive form of brain tumor. In a study published last week in Cell Reports, the team, which includes program director Brad Bernstein, revealed that certain regulatory proteins play a major role in the “self-renewing” cancer stem cells that drive glioblastoma growth.

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  • Cellular archeology

    Paul Goldsmith, May 15th, 2013

    Imagine you’re visiting the Acropolis. You tour the ruins, taking snapshots as you go. Later, at home, you tell your family and friends about your visit and someone, noticing the building’s advanced deterioration, asks: well, how did it get that way? Now, say you knew nothing about the Acropolis, and could only rely on your photos and memory to describe the place. What would you say? Without the rich archeological history of the Acropolis, you’d be missing a huge part of the story.

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  • Inflammatory finding

    Paul Goldsmith, May 2nd, 2013

    To convert food into energy, our bodies rely on a complex network of molecular pathways known broadly as metabolism. Along the path from food to energy, intermediate molecules emerge that form the starting materials for the next step. Traditionally, these intermediates were viewed simply as building blocks — essential for the process, but otherwise inert.

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