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Earlier this month, researchers from the Broad Institute and Massachusetts General Hospital (MGH) published a paper in Nature Methods about a new approach to an established technique. The technique is called ChiP-seq, short for chromatin immunoprecipitation with high-throughput sequencing, and is used to study how protein and DNA interact. The paper's authors are postdoctoral scholars Mazhar Adli and Jiang Zhu and Broad associate member Brad Bernstein. Brad answered five of our questions about his latest paper and his field of interest.

Yeast is as common in the lab as it is in a bakery. It’s a very useful organism because it grows quickly, is easy to culture, and its genetics have been studied extensively. But its very simplicity means it is also has limits – and those limits prompted Broad core member Aviv Regev and her colleagues to think about developing another model for studying cell circuitry.

Regev’s work, which she outlined in a recent talk at the Functional Genomics Data Society in Boston, focuses in part on our cells’ ability to respond to changes.

This afternoon, Ira Flatow will be talking with medical educator Howard Markel about the word genome on Science Friday and I can't wait to tune in! The word has a pretty fascinating 80-year history and we use it all the time in the stories we write and blog entries we post. As such, we've added "genome" as a term to our glossary.