Broad in the news: Ted Stanley’s extraordinary commitment to psychiatric research

Paul Goldsmith, July 25th, 2014

On Tuesday, July 22, the Broad Institute announced an unprecedented commitment of $650 million from philanthropist Ted Stanley to support psychiatric research. Stanley’s gift – the largest ever in psychiatric research and among the largest for scientific research in general – generated a great deal of coverage in the media.

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Broad Paper Vids: Peering into the transcriptome of single cells

Leah Eisenstadt, July 2nd, 2014

The ability to monitor the function and activity of single cells in isolation using RNA sequencing enables researchers to uncover the remarkable heterogeneity of tissues. Using a new microfluidic system to prepare cells for single-cell RNA sequencing, a team of scientists at the Broad Institute and Fluidigm, led by Broad core member Aviv Regev, associate member Hongkun Park, and Fluidigm scientist Andrew May, analyzed the transcriptomes of more than 1,700 primary mouse bone-marrow-derived dendritic cells.

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Broad in the news: New York Times covers landmark heart disease study by Broad researchers and colleagues

Haley Bridger, June 27th, 2014 | Filed under

By scouring the DNA of thousands of patients, researchers at the Broad Institute and Massachusetts General Hospital and their colleagues have discovered four rare mutations in the gene APOC3 that lower triglycerides and reduce a person’s risk of coronary heart disease — dropping it by 40 percent.

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Broad Paper Vids: Study of both common and rare variation yields insight into cardiac arrhythmia

Leah Eisenstadt, June 24th, 2014

In the search for genetic sources of disease risk or genes that control traits, scientists can look for a single mutant gene that causes a rare, Mendelian disease or common DNA alterations that influence the trait in the broader population. But often those approaches remain separate.

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In the news: WBUR talks with Broad scientists on “Brain Matters”

Veronica Meade-Kelly, June 20th, 2014 | Filed under

Steve Hyman, director of the Broad Institute’s Stanley Center for Psychiatric Research, was recently featured in WBUR’s special series “Brain Matters.” The series, which will run through July 24, aims to report “from the front lines of neuroscience,” and is exploring issues and trends in neurological and psychiatric research.

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In the news: Wall Street Journal op-ed balances a troublesome argument

Leah Eisenstadt, June 13th, 2014

The Wall Street Journal this weekend featured an opinion piece by Broad Institute deputy director David Altshuler and Henry Louis Gates, Jr., the director of Harvard's Hutchins Center for African and African American Research. In the piece, Altshuler and Gates present a thoughtful perspective on the history of race as a concept, and the misguided tendency to “view race strictly through the lens of genetic inheritance”.

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Eric Lander, Gad Getz listed among “the one hundred”

Veronica Meade-Kelly, June 4th, 2014

For the past seven years, the Massachusetts General Hospital (MGH) Cancer Center has celebrated the one hundred.” The annual fundraising event recognizes 100 individuals and organizations that are making a difference in the fight against cancer.

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Students Ask : Broadies Answer

Veronica Meade-Kelly, June 3rd, 2014

The Broad’s Office of Education and Outreach, in collaboration with the Cancer Program, is putting tools used for cancer research in students’ hands.

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Broad DREAM Challenge: Help find cancer’s vulnerabilities

Veronica Meade-Kelly, June 2nd, 2014

The Broad-DREAM Gene Essentiality Prediction Challenge has begun. Computational biologists and math wizards of all stripes are invited to enter the competition, which calls on statistically inclined members of the public to develop predictive computational models that reveal which genes are most essential to the survival of various cancer subtypes.

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Broad Paper Vids: From biopsy to bedside

Paul Goldsmith, May 29th, 2014

Whole-exome sequencing—a technique that decodes the genetic information in protein-coding genes—has transformed the understanding and analysis of cancer biology, but the impact of this revolutionary technique has yet to reach patients in the clinic.

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