Blogs

Eric Lander, Gad Getz listed among “the one hundred”

Veronica Meade-Kelly, June 4th, 2014

For the past seven years, the Massachusetts General Hospital (MGH) Cancer Center has celebrated the one hundred.” The annual fundraising event recognizes 100 individuals and organizations that are making a difference in the fight against cancer.

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Students Ask : Broadies Answer

Veronica Meade-Kelly, June 3rd, 2014

The Broad’s Office of Education and Outreach, in collaboration with the Cancer Program, is putting tools used for cancer research in students’ hands.

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Broad DREAM Challenge: Help find cancer’s vulnerabilities

Veronica Meade-Kelly, June 2nd, 2014

The Broad-DREAM Gene Essentiality Prediction Challenge has begun. Computational biologists and math wizards of all stripes are invited to enter the competition, which calls on statistically inclined members of the public to develop predictive computational models that reveal which genes are most essential to the survival of various cancer subtypes.

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Broad Paper Vids: From biopsy to bedside

Paul Goldsmith, May 29th, 2014

Whole-exome sequencing—a technique that decodes the genetic information in protein-coding genes—has transformed the understanding and analysis of cancer biology, but the impact of this revolutionary technique has yet to reach patients in the clinic.

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Now playing: Broad Paper Vids

Veronica Meade-Kelly, May 23rd, 2014

In the coming months, a new video series on the Broad’s popular YouTube channel will introduce viewers to published research – from the scientist’s perspective. In each installment of the “Broad Paper Vids” series, institute researchers will describe the exciting scientific discoveries that have made their way from the Broad to the pages of respected scientific journals.

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Broad core member awarded National Science Foundation’s highest honor

Leah Eisenstadt, April 10th, 2014

Broad Institute core faculty member Feng Zhang has been named the 2014 recipient of the Alan T. Waterman Award from the National Science Foundation. The award, named after the NSF’s first director, is the agency’s highest honor, which annually recognizes an outstanding researcher under the age of 35. Zhang’s award will help support his work to understand how the brain works.

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Glioblastoma’s “stem-like” cells laid bare

Haley Bridger, April 10th, 2014

What: Glioblastoma, the most common and most aggressive form of brain cancer in adults, remains effectively incurable. Evidence suggests that “stem-like” cells help drive this difficult-to-treat disease. These cells may possess properties that give them the ability to resist treatment and drive cancer’s growth, but pinpointing them and understanding the circuitry that makes them behave the way they do has been a major challenge.

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Studies converge on ALS

Veronica Meade-Kelly, April 4th, 2014

What: Researchers from the Broad Institute, the Harvard Stem Cell Institute (HSCI), and Boston Children’s Hospital (BCH) used an eclectic combination of cutting-edge technologies to determine what’s going wrong at the molecular level in the neurodegenerative disease amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. Their research, published online this week in two separate Cell journals, sheds light on the mechanisms that lead to the disease and highlights potential targets for new treatments.

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Kerstin Lindblad-Toh receives major award from Swedish Research Council

Paul Goldsmith, March 31st, 2014

This week, Broad scientific director of vertebrate genome biology Kerstin Lindblad-Toh became one of the first recipients of a new long-term research grant from the Swedish Research Council. The program, known as Grants for Distinguished Professors, provides Swedish scientists with 10 years of flexible funding to support ambitious, long-term projects. Lindblad-Toh is one of only nine researchers selected to receive the inaugural award.

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Insights into drug resistance for a rare leukemia

Haley Bridger, March 3rd, 2014

What: For patients with T cell acute lymphoblastic leukemia (T-ALL), a rare form of blood cancer that mainly affects children and young adults, drug resistance poses a major threat to a promising treatment option currently in clinical trials. About half of patients with T-ALL have mutations in NOTCH1, but drugs that target this gene have so far produced only short-lived effects: at first, the cancer seems to respond, but in a short period of time, T-ALL returns.

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