Shuangye Yin is a computational biologist in the Genome Sequencing and Analysis Program at the Broad Institute. His work focuses on developing computational methods to reconstruct an organism’s genome from gigantic amounts of sequencing data emerging from next-generation sequencing technologies.
Yin works on the design and implementation of computer programs known as algorithms. He also conducts rapid prototyping on sequencing data sets and analysis of data sets.
Yin joined the Broad in January 2011 after obtaining a Ph.D. in physics from Georgia Institute of Technology and completing four years of postdoctoral training in the Department of Biochemistry and Biophysics at the University of North Carolina at Chapel Hill.Select Publications
Yin S, Proctor EA, Lugovskoy AA, Dokholyan NV. Fast screening of protein surfaces using geometric invariant fingerprints. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16622-6. Epub 2009 Sep 17.
Yin S, Ding F, Dokholyan NV. Eris: an automated estimator of protein stability. Nat Methods. 2007 Jun;4(6):466-7.
Yin S, Moro R, Xu X, de Heer WA. Magnetic enhancement in cobalt-manganese alloy clusters. Phys Rev Lett. 2007 Mar 16;98(11):113401. Epub 2007 Mar 15.