Elinor Karlsson is a postdoctoral scientist at the Broad Institute. A member of the Sabeti Lab, Karlsson conducts research that is rooted in recent evolutionary history. By combining tests for natural selection with genome-wide association studies, she aims to identify genes, pathways, and functional variants underlying polygenic diseases, and translate these discoveries into advances in human health care. Karlsson is currently using natural selection and association to find the underlying genetic causes of obsessive-compulsive disorder (using dogs as a model organism) and cholera resistance in humans.
Karlsson has a special interest in using natural selection to identify trait-associated genetic variants in humans and dogs. For her doctoral thesis, she developed new methods for genome-wide association tailored to the unique population structure of the domestic dog. This research helped uncover some of the genetic causes of disease in purebred dogs. In addition, she has also analyzed genomic data from mice, cats, sea squirts, microorganisms, and infectious diseases such as malaria, among others.
Karlsson is currently a postdoctoral fellow at Harvard University. In June of 2013, she was awarded the Charles A. King Trust Postdoctoral Fellowship. Karlsson received her B.A. in biochemistry/cell biology from Rice University, and earned her Ph.D. in bioinformatics from Boston University.Last updated date: September 2013