Hepatitis C Virus Portal

Hepatitis C Virus (HCV) Classification

ICTV Group: Unassigned
Baltimore Group: Group IV [(+) ssRNA, no DNA stage]
Family: Flaviviridae
Genus: Hepacivirus
Species: Hepatitis C virus (HCV)

Summary

Hepatitis C is an emerging infection and a burgeoning worldwide public health problem, with 170 million infected and an estimated 20 million deaths in the coming decades. HCV is a major cause of liver cirrhosis, liver failure and hepatocellular carcinoma, infecting an estimated 170 million individuals worldwide [1]. Furthermore, HCV has emerged as an important cause of morbidity and mortality in HIV-infected subjects [2,3]. While drug treatments are available, clear limitations in access and efficacy require concerted efforts to develop effective prophylactic and therapeutic vaccines.

Funding Information

This sequencing project was supported by the National Institute of Allergy and Infectious Disease, National Institutes of Health funded Genome Sequencing Center for Infectious Diseases at the Broad Institute.