Descriptions

Outline

Click the species name for a description of the organism

Streptomyces sp. Mg1

Isolated from a glacier in Alaska, Streptomyces sp. Mg1 was chosen to represent geographical diversity among actinomycetes.

Streptomyces sp. SPB74

As the symbiont of a beetle, Streptomyces sp. SPB74 was chosen to represent ecological diversity among actinomycetes.

Streptomyces clavuligerus ATCC 27064

S. clavuligerus produces the beta-lactamase inhibitor clavulanate, which is one component of the widely used antibacterial combination Augmentin.

Streptomyces pristinaespiralis ATCC 25486

S. pristinaespiralis produces the pristinamycins, which are modified semisynthetically to form the antibacterial combination Synercid.

Streptomyces sviceus ATCC 29083

S. sviceus produces oxidative enzymes that 'tailor' small molecules and will therefore be useful in efforts to diversify their structures in vitro.

Streptomyces ghanaensis ATCC 14672

S. ghanaensis is a high-GC Gram-positive bacterium, which produces moenomycin, an antibiotic that targets the transglycosylation step of bacterial cell wall biosynthesis.

Streptomyces roseosporus NRRL 15998 and NRRL 11379

S. roseosporus is a high-GC Gram-positive bacterium. Isolated from Mount Ararat in Turkey, S. roseosporus produces the antibiotic daptomycin (Cubicin), which belongs to the newest class of antibiotics in clinical use.

Streptomyces albus J1074

S. albus is a high-GC Gram-positive bacterium, and is widely used as a host for producing small molecules and enzymes from other actinomycetes.

Streptomyces sp. AA4

Streptomyces sp. AA4 is a high-GC Gram-positive bacterium from an order known for its prolific production of small molecule natural products, Actinomycetales. Actinomycetes are the source of numerous clinically-used antibiotics, anticancer agents, and immunosuppressive agents. Streptomyces sp. AA4 is naturally resistant to 15 antibiotics, so its genome sequence is likely to reveal how soil bacteria may serve as a reservoir for naturally occurring mechanisms of antibiotic resistance.

Streptomyces sp. Strain C

Streptomyces sp. Strain C is a high-GC Gram-positive bacterium from an order known for its prolific production of small molecule natural products, Actinomycetales. Actinomycetes are the source of numerous clinically-used antibiotics, anticancer agents, and immunosuppressive agents. Isolated from a Chinese soil sample, Streptomyces sp. Strain C was chosen to represent geographical diversity among actinomycetes.

Streptomyces sp. SPB78

Streptomyces sp. SPB78 is a high-GC Gram-positive bacterium from an order known for its prolific production of small molecule natural products, Actinomycetales. Actinomycetes are the source of numerous clinically-used antibiotics, anticancer agents, and immunosuppressive agents. As the symbiont of a beetle, Streptomyces sp. SPB78 was chosen to represent ecological diversity among actinomycetes.

Streptomyces griseoflavus Tü4000

Streptomyces griseoflavus Tü4000 is a high-GC Gram-positive bacterium from an order known for its prolific production of small molecule natural products, Actinomycetales. Actinomycetes are the source of numerous clinically-used antibiotics, anticancer agents, and immunosuppressive agents. S. griseoflavus produces oxidative enzymes that 'tailor' small molecules and will therefore be useful in efforts to diversify their structures in vitro.

Streptomyces hygroscopicus ATCC 53653

Streptomyces hygroscopicus ATCC 53653 is a high-GC Gram-positive bacterium from an order known for its prolific production of small molecule natural products, Actinomycetales. Actinomycetes are the source of numerous clinically-used antibiotics, anticancer agents, and immunosuppressive agents. S. hygroscopicus produces oxidative enzymes that 'tailor' small molecules and will therefore be useful in efforts to diversify their structures in vitro.

Streptomyces lividans TK24

Streptomyces lividans TK24 is a high-GC Gram-positive bacterium from an order known for its prolific production of small molecule natural products, Actinomycetales. Actinomycetes are the source of numerous clinically-used antibiotics, anticancer agents, and immunosuppressive agents. S. lividans is widely used as a host for producing small molecules and enzymes from other actinomycetes.

Streptomyces viridochromogenes DSM 40736

Streptomyces viridochromogenes DSM 40736 is a high-GC Gram-positive bacterium from an order known for its prolific production of small molecule natural products, Actinomycetales. Actinomycetes are the source of numerous clinically-used antibiotics, anticancer agents, and immunosuppressive agents. S. viridochromogenes produces phosphinothricin, a member of the phosphonate family of natural products, which includes several potent antibiotics.

Micromonospora carbonacea var. Africana ATCC 39149

Micromonospora carbonacea var. Africana ATCC 39149 is a high-GC Gram-positive bacterium from an order known for its prolific production of small molecule natural products, Actinomycetales. Actinomycetes are the source of numerous clinically-used antibiotics, anticancer agents, and immunosuppressive agents. M. carbonacea produces everninomicin, chloramphenicol, and a glycosylated thiostrepton, three antibiotics that target the ribosome and inhibit protein synthesis.