M. tuberculosis
Gene Search
Polymorphism Report: XDR-TB Strains
| Protein-Coding Mutations: SNPs Unique to XDR | ||||||||||||||||
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| F11 Location | F11 Gene (H37Rv) | Mutation | Annotation | Base | Alignment | |||||||||||
| F11 | Δ | DNA | Protein | |||||||||||||
| 7671 | TBFG_10006 (Rv0006) | A90V | DNA gyrase subunit A gyrA | C | T |  |
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| 1276085 | TBFG_11169 (Rv1145) | L25I | transmembrane transport protein mmpL13a | C | A | |
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| 760518 | TBFG_10676 (Rv0663) | Y207Y | arylsulfatase atsD (aryl-sulfate sulphohydrolase) | C | T | |
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| 764871 | TBFG_10681 (Rv0667) | D441G | DNA-directed RNA polymerase beta subunit rpoB | A | G | |
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| 764922 | TBFG_10681 (Rv0667) | L458P | DNA-directed RNA polymerase beta subunit rpoB | T | C | |
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| 766884 | TBFG_10681 (Rv0667) | I1112T | DNA-directed RNA polymerase beta subunit rpoB | T | C | |
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| 1477013 | TBFG_14046 (MTB000019) | A1401G | ribosomal RNA 16S rrs | A | G | |
N/A | |||||||||
| 2254286 | TBFG_12032 (Rv2000) | L275P | hypothetical protein | T | C | |
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| 4282272 | TBFG_13840 (Rv3806c) | V188A | conserved integral membrane protein | T | C | |
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| 3893152 | TBFG_13496 (Rv3459c) | A84A | 30S ribosomal protein S11 rpsK | C | G | |
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| 3902861 | TBFG_13508 (Rv3471c) | D64E | hypothetical protein | C | A | |
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| 3748038 | TBFG_13376 (Rv3343c) | G418W | PPE family protein | G | T | |
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| Protein-Coding Mutations: Indels Unique to XDR | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| F11 Location | F11 Gene (H37Rv) | Annotation | Frameshift | Alignment | ||||||||||
| DNA | Protein | |||||||||||||
| 2303400 | TBFG_12080 (Rv2043c) | pyrazinamidase/nicotinamidase pncA | Yes | |
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| Non-Protein-Coding Mutations Unique to XDR | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| F11 Location | Mutation | Left Gene | Right Gene | Distance Away From: | Intergenic Alignment | ||||||
| F11 | Δ | F11 (H37Rv) | Annotation | F11 (H37Rv) | Annotation | Left Direction | Left Gene | Right Gene | Right Direction | ||
| 668157 | C | A | TBFG_10581 (Rv0571c) | hypothetical protein | TBFG_10582 (Rv0572c) | hypothetical protein | ← | 111 | 113 | ← | |
| 4069433 | T | C | TBFG_13647 (Rv3616c) | conserved alanine and glycine rich protein | TBFG_13648 (Rv3617) | epoxide hydrolase ephA | ← | 55 | 1303 | → | |