M. tuberculosis
Gene Search
Polymorphism Report: MDR-TB Strains
| Protein-Coding Mutations: SNPs Unique to MDR | ||||||||||||||||
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| F11 Location | F11 Gene (H37Rv) | Mutation | Annotation | Base | Alignment | |||||||||||
| F11 | Δ | DNA | Protein | |||||||||||||
| 1005429 | TBFG_10916 (Rv0897c) | T271M | hypothetical oxidoreductase | C | T |  |
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| 2201503 | TBFG_11969 (Rv1940) | G215S | riboflavin biosynthesis protein ribA1 (GTP cyclohydrolase II) | G | A | |
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| 764870 | TBFG_10681 (Rv0667) | D441Y | DNA-directed RNA polymerase beta subunit rpoB | G | T | |
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| 765027 | TBFG_10681 (Rv0667) | N493S | DNA-directed RNA polymerase beta subunit rpoB | A | G | |
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| 2303459 | TBFG_12080 (Rv2043c) | G132A | pyrazinamidase/nicotinamidase pncA | G | C | |
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| 4422308 | TBFG_13956 (Rv3921c) | I256V | conserved transmembrane protein | A | G | |
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| 2687873 | TBFG_12408 (Rv2383c) | P420P | phenyloxazoline synthase mbtB | C | G | |
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| 3651352 | TBFG_13288 (Rv3259) | P86P | hypothetical protein | G | A | |
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| 2881156 | TBFG_12565 (Rv2545) | P19L | hypothetical protein | C | T | |
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| Protein-Coding Mutations: Indels Unique to MDR | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| F11 Location | F11 Gene (H37Rv) | Annotation | Frameshift | Alignment | ||||||||||
| DNA | Protein | |||||||||||||
| 1577028 | TBFG_11425 (Rv1396c) | PE-PGRS family protein | Yes | |
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| Non-Protein-Coding Mutations Unique to MDR | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| F11 Location | Mutation | Left Gene | Right Gene | Distance Away From: | Intergenic Alignment | ||||||
| F11 | Δ | F11 (H37Rv) | Annotation | F11 (H37Rv) | Annotation | Left Direction | Left Gene | Right Gene | Right Direction | ||
| 2983290 | T | C | TBFG_12662 (Rv2643) | hypothetical protein | TBFG_12663 (Rv2645) | hypothetical protein | → | 1141 | 150 | → | |