M. tuberculosis
Gene Search
Polymorphism Report: MDR/XDR-TB Strains
| Protein-Coding Mutations: SNPs Shared by MDR and XDR | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| F11 Location | F11 Gene (H37Rv) | Mutation | Annotation | Base | Alignment | |||||||||||
| F11 | Δ | DNA | Protein | |||||||||||||
| 24226 | TBFG_10020 (Rv0020c) | L440L | hypothetical protein | C | T |  |
 |
|||||||||
| 2192626 | TBFG_11962 (Rv1933c) | V196A | acyl-CoA dehydrogenase fadE18 | T | C | |
|
|||||||||
| 122241 | TBFG_10104 (Rv0103c) | G23S | cation transporter ATPase B ctpB | G | A | |
|
|||||||||
| 243436 | TBFG_10206 (Rv0204c) | C48R | conserved transmembrane protein | T | C | |
|
|||||||||
| 3284470 | TBFG_12950 (Rv2936) | R262G | daunorubicin-dim-transport ATP-binding protein ABC transporter drrA | A | G | |
|
|||||||||
| 4260430 | TBFG_13829 (Rv3795) | M290V | integral membrane indolylacetylinositol arabinosyltransferase embB | A | G | |
|
|||||||||
| 2414963 | TBFG_12171 (Rv2141c) | G109G | hypothetical protein | C | A | |
|
|||||||||
| 4422999 | TBFG_13956 (Rv3921c) | Y25Y | conserved transmembrane protein | C | T | |
|
|||||||||
| 3752300 | TBFG_13378 (Rv3345c) | T980T | PE-PGRS family protein | C | T | |
|
|||||||||
| 1538476 | TBFG_11392 (Rv1361c) | Q286R | PPE family protein | A | G | |
|
|||||||||
| 1280646 | TBFG_11173 (Rv1148c) | A306A | hypothetical protein | G | C | |
|
|||||||||
| 1280649 | TBFG_11173 (Rv1148c) | Q305Q | hypothetical protein | G | A | |
|
|||||||||
| Protein-Coding Mutations: Indels Shared by MDR and XDR | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| F11 Location | F11 Gene (H37Rv) | Annotation | Frameshift | Alignment | ||||||||||
| DNA | Protein | |||||||||||||
| 3950351 | TBFG_13542 (Rv3508) | PE-PGRS family protein | No | |
|
|||||||||
| 4420920 | TBFG_13954 (Rv3919c) | glucose-inhibited division protein B gid | Yes | |
|
|||||||||
| Non-Protein-Coding Mutations Shared by MDR and XDR | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| F11 Location | Mutation | Left Gene | Right Gene | Distance Away From: | Intergenic Alignment | ||||||
| F11 | Δ | F11 (H37Rv) | Annotation | F11 (H37Rv) | Annotation | Left Direction | Left Gene | Right Gene | Right Direction | ||
| 1678069 | T | A | TBFG_11511 (Rv1482c) | hypothetical protein | TBFG_11512 (Rv1483) | 3-oxoacyl-[acyl-carrier protein] reductase fabG1 | ← | 133 | 8 | → | |
| 2988500 | T | G | TBFG_12668 (no ortholog) | hypothetical phiRv2 prophage protein | TBFG_12669 (Rv2653c) | hypothetical phiRv2 prophage protein | ← | 122 | 45 | ← | |
| 2988527 | C | A | TBFG_12668 (no ortholog) | hypothetical phiRv2 prophage protein | TBFG_12669 (Rv2653c) | hypothetical phiRv2 prophage protein | ← | 149 | 18 | ← | |
| 4340484 | T | C | TBFG_13890 (Rv3854c) | monooxygenase ethA | TBFG_13891 (Rv3855) | "transcriptional regulatory repressor protein, tetR-family ethR" | ← | 11 | 65 | → | |