Polymorphism Report: DS-TB Strains

 

Protein-Coding Mutations: SNPs Unique to DS
F11 Location F11 Gene (H37Rv) Mutation Annotation Base Alignment
F11 Δ DNA Protein
60081 TBFG_10056 (Rv0057) L28M hypothetical protein C A
479216 TBFG_10401 (Rv0397) R77R 13E12 repeat family protein G C
1596003 TBFG_11444 (Rv1415) G422G riboflavin biosynthesis protein ribA2: GTP cyclohydrolase II + 3,4-dihydroxy-2-butanone 4-phosphate synthase C T
601489 TBFG_10518 (Rv0507) V382V transmembrane transport protein mmpL2 G A
1649824 TBFG_11487 (Rv1459c) P318S conserved integral membrane protein C T
795247 TBFG_10705 (Rv0691c) P61S hypothetical transcriptional regulatory protein C T
3189498 TBFG_12882 (Rv2866) L49L hypothetical protein G A
4159851 TBFG_13734 (Rv3703c) A14A hypothetical protein G A
4361127 TBFG_13905 (Rv3870) T549T conserved transmembrane protein C T
4420920 TBFG_13954 (Rv3919c) H96R glucose-inhibited division protein B gid A G
2687390 TBFG_12408 (Rv2383c) A581A phenyloxazoline synthase mbtB C T
2973548 TBFG_12653 (Rv2634c) G747G PE-PGRS family protein C A

 

Protein-Coding Mutations: Indels Unique to DS
F11 Location F11 Gene (H37Rv) Annotation Frameshift Alignment
DNA Protein
278596 TBFG_10234 (Rv0232) hypothetical transcriptional regulatory protein, tetR/acrR-family Yes

 

Non-Protein-Coding Mutations Unique to DS
F11 Location Mutation Left Gene Right Gene Distance Away From: Intergenic Alignment
F11 Δ F11 (H37Rv) Annotation F11 (H37Rv) Annotation Left Direction Left Gene Right Gene Right Direction
717183 C T TBFG_10631 (Rv0620) galactokinase galK TBFG_10632 (Rv0621) hypothetical membrane protein 148 238
3842850 G C TBFG_13445 (Rv3411c) inosine-5-monophosphate dehydrogenase guaB2 TBFG_13446 (Rv3412) hypothetical protein 39 168