Listeria Strain Descriptions

Strain ID(s)Description
J0161; FSL R2-499This serotype 1/2a strain was isolated from a case in a human listeriosis outbreak in 2000 linked to consumption of sliced turkey (Olsen et. al 2005). The outbreak was traced back to a single food processing plant in the US. This is one of the few lineage II strains associated with human listeriosis. Strain J0161 is also known as FSL R2-499.
10403SThis serotype 1/2a strain is used by the majority of investigators in the U.S. studying the pathogenesis of L. monocytogenes. 10403S is a streptomycin resistant isolate of strain 10403. The parental strain 10403 was first reported by Edman et al. (1968) as an isolate from a human skin lesion obtained from Montana State University and is further described in Bishop et al. (1987).
FSL J1-194This serotype 1/2b strain, isolated from a sporadic human listeriosis case, is a representative of ribotype DUP-1042B. This ribotype has been linked to two human listeriosis outbreaks and is also responsible for a number of sporadic human listeriosis outbreaks.
FSL R2-503This serotype 1/2b strain, which is also known as G6054, was responsible for a gastrointestinal listeriosis outbreak in the US in 1994. Analysis of this strain will provide insight into the differences between strains causing systemic versus diarrheal disease.
J2818This serotype 1/2a strain was isolated from food associated with a case in a human listeriosis outbreak in 2000 linked to consumption of sliced turkey (Olsen et. al 2005). The outbreak was traced back to a single food processing plant in the US. This is one of the few lineage II strains associated with human listeriosis.
HPB2262This serotype 4b strain was isolated from one of hundreds of cases of febrile gastrointestinal illness among students and staff who had eaten at one of two school cafeterias in Northern Italy in 1997. Definitive cause of the illness is not known, but Listeria is the best suspect. This strain, like FSL R2-503, is interesting because Listeria is rarely associated with these symptoms (Aureli et al 2000). (This strain was formerly referred to as Aureli 1997.)
FSL N1-017This serotype 4b strain has a ribotype that is exclusively associated with foods (Gray et al., 2004) FSL N1-017 was isolated from trout in brine and is not associated with any human disease cases.
FSL J2-071Rare lineage III L. monocytogenes strains are predominantly associated with animal disease, are highly diverse and represent rare serotypes. This serotype 4c isolate from an animal clinical case represents lineage IIIA, having the most common ribotype in the lineage, DUP-1061A.
FSL N3-165This serotype 1/2a1 soil isolate is a representative of ribotype DUP-1045A. This ribotype is found in the environment and animals without disease but not in diseased animals. (Nightingale et al., 2004).
F6900This serotype 1/2a strain was isolated from a single case of human listeriosis in 1989 linked to consumption of processed meat . The contaminated food was made at the same processing plant from which strains J0161 and J2818 came 11 years later.
LO28This serotype 1/2c lab strain was used for many early virulence studies and has been widely distributed and published on. Its genome sequence would be of considerable interest to the research community.
FSL J2-003This serotype 1/2a strain has ribotype DUP-1039C, a ribotype that is one of the most common subtypes associated with ruminant listeriosis cases and is also commonly isolated in feces of healthy ruminants and the farm environment (Nightingale et al., 2004).
FSL J1-175This is a serotype 1/2b isolate not associated with any disease. This strain was isolated from water, not associated with human disease outbreak or case.
FSL-F2-515This serotype 1/2a1 strain bears ribotype DUP-1062A. This ribotype is one of the most common subtypes found among food isolates, but rarely causes human disease (Gray et al., 2004).
FSL J2-064This serotype 1/2b strain carries one of the most common ribotypes found among food isolates, DUP-1052, and also is commonly associated with human disease (Gray et al., 2004).
FSL J1-208This is the first serotype 4a Listeria genome sequence. This isolate, from an animal clinical case, is from the most common lineage IIIB ribotype: DUP-10142.

References

  • Aureli P., G. C. Fiorucci, D. Caroli, G. Marchiaro, O. Novara, L. Leone, S. Salmaso. An outbreak of febrile gastroenteritis associated with corn contaminated by Listeria monocytogenes. N Engl J Med. 342(17):1236-41.
  • Bishop, D. K., and D. J. Hinrichs. 1987. Adoptive transfer of immunity to Listeria monocytogenes. The influence of in vitro stimulation on lymphocyte subset requirements. J. Immunol. 139:2005-2009.
  • Gray, M. J., R. N. Zadoks, E. D. Fortes, B. Dogan, S. Cai, Y. Chen, V. N. Scott, D. E. Gombas, K. J. Boor, and M. Wiedmann. 2004. Listeria monocytogenes isolates from foods and humans form distinct but overlapping populations. Appl. Environ. Microbiol. 2004 Oct;70(10):5833-41.
  • Edman, D.C., Pollock, M.B. and E. R. Hall. 1968. Listeria monocytogenes L Forms I. Induction, Maintenance, and Biological Characteristics. J. Bacteriology 96:352-357
  • Nightingale, K. K., Y. H. Schukken, C. R. Nightingale, E. D. Fortes, A. J. Ho, Z. Her, Y. T. Grohn, P. L. McDonough, and M. Wiedmann. 2004. Ecology and transmission of Listeria monocytogenes in ruminants and the farm environment. Appl. Env. Microbiol. 70:4458-4467.
  • Olsen SJ, Patrick M, Hunter SB, Reddy V, Kornstein L, MacKenzie WR, Lane K, Bidol S, Stoltman GA, Frye DM, Lee I, Hurd S, Jones TF, LaPorte TN, Dewitt W, Graves L, Wiedmann M, Schoonmaker-Bopp DJ, Huang AJ, Vincent C, Bugenhagen A, Corby J, Carloni ER, Holcomb ME, Woron RF, Zansky SM, Dowdle G, Smith F, Ahrabi-Fard S, Ong AR, Tucker N, Hynes NA, Mead P. Multistate outbreak of Listeria monocytogenes infection linked to delicatessen turkey meat. Clin Infect Dis. 2005 Apr 1;40(7):962-7.