Cryptococcus neoformans Serotype B Database
Cryptococcus neoformans, a ubiquitous human pathogen, is the leading cause of infectious meningitis. The Cryptococcus species have been diverging over the past 40 million years into three distinct varieties and four serotypes: the predominantly opportunistic pathogens C. neoformans var. neoformans (serotype D) and C. neoformans var. grubii (serotype A) and the primary pathogen C. neoformans var. gattii (serotypes B and C). Serotype B isolate R265 caused an outbreak on Vancouver Island in Canada that involved more than 50 infections in otherwise healthy human patients, with at least four fatalities (Fyfe, Black et al. 2002). The outbreak isolate R265 has a VGII molecular genotype by PCR fingerprinting, which differs from the VGI molecular genotype of strain WM276 (J. Kronstad, personal communication).
ToolsBLAST Search: Find similarities to other sequences Feature Search: Search and view annotated features on the sequence Browse Regions: Retrieve DNA, find clones, and graphically view sequence regions Gene Index: Find genes by a variety of methods Genome Statistics:View basic statistics about genome size, gene density, etc Download Data: Download sequence, genes, markers, and other genome data InformationContact Us:Addresses for contacting the Broad Institute Related Links:Links to sites related to the Cryptococcus neoformans Serotype B genome project |
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