Descriptions

Outline

Click the species name for a description of the organism

Brucella sp. NVSL 07-0026

A novel Brucella isolate associated with stillbirth in non-human primates. The genomic DNA for this isolate was provided by Renee Tsolis, University of California, Davis. The isolation of the strain is described by Schlabritz-Loutsevitch et al (2009)

Brucella abortus bv.5 B3196 (also known as NCTC10504; ATCC 23452; BCCN R8)

This is the Brucella abortus biovar 5 reference strain originally isolated from bovine uterine discharge at the Veterinary Investigation Centre, Bristol, England in 1959 (Meyer and Morgan 1973). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom. Reference: Meyer,M.E et al (2009)

Brucella abortus bv. 6 str. 870

Strain also known as NCTC10505; ATCC 23453; BCCN R9. This is the Brucella abortus biovar 6 reference strain originally isolated from a bovine foetus in Africa in 1959 and supplied to the VLA by Dr R. Dijkstra, Leeuwarden, Netherlands (Meyer and Morgan 1973). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella abortus bv. 4 str. 292

Strain also known as 39/94. This is the Brucella abortus biovar 4 reference strain originally isolated from a bovine foetus at the Veterinary Investigation Centre, Oban, Scotland in 1960 (Meyer and Morgan 1973). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella abortus bv. 3 str. Tulya

Strain also known as NCTC10502; ATCC 23450; BCCN R6. This is the Brucella abortus biovar 3 reference strain originally isolated from a human in Uganda in 1958 by Dr K.W. Jones, Kampala, Uganda (Meyer and Morgan 1973). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella abortus bv. 2 str. 86/8/59

Strain also known as NCTC10501; ATCC 23449; BCCN R5. This is the Brucella abortus biovar 2 reference strain originally isolated from a bovine foetus at the Veterinary Investigation Centre, Newcastle, England in 1959 (Meyer and Morgan 1973). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella suis bv. 5 513

Strain also known as NCTC11996; BCCN R21. This is the Brucella suis biovar 5 reference strain originally isolated from a rodent in the former Soviet Union (Vershilova et al. 1983; Corbel 1984). Note that the isolate is described in some literature as 514. The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella suis bv. 3 str. 686

Strain also known as NCTC10511; ATCC 23446; BCCN R14. This is the Brucella suis biovar 3 reference strain originally isolated from a pig in the USA (Meyer and Morgan 1973). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella pinnipedialis M163/99/10

Strain also known as UK9/99. This is a representative of Brucella pinnipedialis subgroup associated with hooded seals and was originally isolated from a hooded seal (Cystophora cristata) in the UK (Groussaud et al. 2007). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella pinnipedialis B2/94

Strain also known as NCTC 12890. This is the Brucella pinnipedialis type strain originally isolated from the spleen of a common seal (Phoca vitulina) in the UK. (Foster et al. 2007). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella ceti M644/93/1

Strain also known as 14/94. This is a representative of Brucella ceti subgroup associated with dolphins and was originally isolated from a common dolphin (Delphinus delphis) in the UK (Groussaud et al. 2007). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella ceti M13/05/1

Strain also known as UK3/05. This is a representative of Brucella ceti subgroup associated with dolphins and was originally isolated from a striped dolphin (Stenella coeruleoalba) in the UK (Groussaud et al. 2007). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella sp. 83/13

This is an example of a group of strains held at the Veterinary Laboratories Agency, United Kingdom, described as being isolated from rodents in Queensland, Australia and mentioned briefly in Corbel MJ. 1984 (Corbel 1984). Preliminary characterization of the isolates suggests they represent a novel Brucella species rather distantly related to all currently described species (A.M. Whatmore, unpublished data). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella pinnipedialis M292/94/1

Strain also known as 39/94. This is a representative of Brucella pinnipedialis originally isolated from a common seal (Phoca vitulina) in the UK (Groussaud et al. 2007). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella melitensis bv. 1 str. Rev.1

Strain also known as BCCN V4a. Live vaccine strain originally derived following by repeat passage of virulent Brucella melitensis 6056 (M. Ruiz-Castaneda, Mexico City, Mexico) on medium containing streptomycin by Elberg and colleagues in the 1950s (Herzberg and Elberg 1953). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom from a strain provided to the VLA by Prof. Elberg in 1964.

Brucella neotomae 5K33

Strain also known as NCTC10084; ATCC 23459; BCCN R16. This is the Brucella neotomae type strain originally isolated from a desert wood rat in the USA (Stoenner and Lackman 1957). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella melitensis bv. 3 str. Ether

Strain also known as NCTC10509; ATCC 23458; BCCN R3. This is the Brucella melitensis biovar 3 reference strain originally isolated by Prof. G. Garini (Univ. di Firenze, Italy) from a goat in Italy in 1961 (Meyer and Morgan 1973). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella ceti M490/95/1

Strain also known as 14/95. This is a representative of the Brucella ceti subgroup largely associated with porpoises but was originally isolated from a common seal (Phoca vitulina) in the UK (Groussaud et al. 2007). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella ceti B1/94

Strain also known as NCTC 12891. This is the Brucella ceti type strain originally isolated from a skin lesion on a harbour porpoise (Phocoena phocoena) in the UK. (Groussaud et al. 2007). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella abortus bv. 9 str. C68

Strain also known as NCTC10507; ATCC 23455; BCCN R11. This is the Brucella abortus biovar 9 reference strain originally isolated from a bovine foetus at the Veterinary Investigation Centre, Aberdeen, Scotland in 1958 (Meyer and Morgan 1973). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella melitensis bv. 2 str. 63/9

Strain also known as NCTC10508; ATCC 23457; BCCN R2. This is the Brucella melitensis biovar 2 reference strain (Meyer and Morgan 1973). Although frequently described in the literature as originating from a goat in Turkey, NCTC descriptions and VLA records indicate the strain was isolated by Mathur in India in 1963. The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella sp. F5/99

Strain also known as 2-1350, NVSL 92-19953, Muu. This is one of the original Brucella isolates from marine mammals obtained from the aborted foetus of a bottlenose dolphin (Tursiops truncatus) in the USA in 1992 (Ewalt et al. 1994). The isolate was chosen for sequencing as a representative of ST27 that has recently been found associated with severe and atypical human infections (Whatmore et al. 2008). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom. Author List: Adrian M. Whatmore, Lorraine L. Perrett, David O'Callaghan

Brucella abortus bv. 1 S19

Strain also known as NCTC 8038. Vaccine strain originally provided to the VLA in 1943 by the US Department of Agriculture. This strain was deposited in the NCTC by Stableforth of the (now) VLA, Weybridge, UK in 1949. This was before USDA decided to replace the diverse vaccine stocks circulating with an erythritol sensitive isolate, in 1956. Although erythritol sensitivity, caused by the presence of the eryCD deletion (Sangari, García-Lobo and Agüero, FEMS Microbiol Lett 121:337-342), has been regarded as one of the attenuating factors of S19, it is not present in NCTC 8038 (Sangari FJ, personal communication). The genomic DNA for this isolate was provided by Félix J. Sangari of Universidad de Cantabria, Santander, Spain.

Brucella melitensis bv. 1 16M

Strain Description: Type strain reported to be originally isolated from a goat (Meyer ME & Morgan WJB. 1973. Brucella Strain also known as ATCC 23456T; NCTC 10094T; BCCN R1T. Designation of the neotype strains and of biotype reference strains of the genus Brucella Meyer and Shaw. Int. J. Syst. Bact. 23:135-141) and provided to the VLA by the Bureau of Animal Industry, Washington, USA in 1952. The culture sequenced represented a vial from a bulk lyophilisation at the VLA in 1955. The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom. Author List: Adrian M. Whatmore, Lorraine L. Perrett, D. O'Callaghan

Brucella suis bv. 4 40

Strain also known as NCTC11364; ATCC 23447; BCCN R15; 40/67. This is the Brucella suis biovar 4 reference strain originally isolated from a reindeer in the former Soviet Union (Meyer and Morgan 1973). The genomic DNA for this isolate was provided by Adrian Whatmore of the Veterinary Laboratories Agency, United Kingdom.

Brucella abortus bv.1

Genusspeciesbiovarstrain
Brucella abortus bv.1 NI435a
Brucella abortus bv.1 NI474
Brucella abortus bv.1 NI486
Brucella abortus bv.1 NI488
Brucella abortus bv.1 NI010
Brucella abortus bv.1 NI016
Brucella abortus bv.1 NI021
Brucella abortus bv.1 NI259

These strains are bovine isolates obtained in Northern Ireland (1991). Northern Ireland remains the only part of the United Kingdom where brucellosis of cattle, caused by Brucella abortus, remains endemic. Northern Ireland is only 5400 square miles in size and the current endemic disease situation is thought to reflect a very limited number of introductions. This work will serve as a model for the development of epidemiological tools applicable in local disease control in other areas of the world and add to knowledge about the evolution and diversity of Brucella at the local level.

Citations

Natalia E. Schlabritz-Loutsevitch, Adrian M. Whatmore, Christine R. Quance, Mark S. Koylass, L. Bill Cummins, Edward J. Dick Jr, Cathy L. Snider, David Cappelli, Jeffrey L. Ebersole, Peter W. Nathanielsz, Gene B. Hubbard. Journal of Medical Primatology. (2009) J Med Primatol. 38(1):70-3

Meyer ME, Morgan WJB (1973) Designation of Neotype Strains and of Biotype Reference Strains for Species of the Genus Brucella Meyer and Shaw. Int J Syst Bacteriol 23(2): 135-141.