Acinetobacter baumannii Fast Track Database

Project Information

Acinetobacter baumannii is a Gram-negative human pathogen responsible for an increasing number of nosocomial infections among hospital patients worldwide. Its emergence as a significant hospital pathogen is due to its capacity to survive and spread within the hospital environment, its ability to cause prolonged asymptomatic infections within the host, and its propensity to develop multidrug resistance.

In this project we sequenced a group of five bacterial isolates obtained from a single hospital in the Boston area as part of our mission to develop and maintain a robust fast-track sequencing and analysis pipeline capable of rapidly responding to outbreaks of bacterial infectious disease. Using a whole genome sequencing approach will enable us to understand the diversity and the phylogenetic relationship between these isolates as well as lead to insights in the evolution of these strains within the hospital environment.

For comparative analysis, we also downloaded 9 closely related genomes from GenBank and included them in this site.

Upon sequencing, we determined that one of the five isolates (Ab55555) turned out to be a Stenotrophomonas maltophilia strain. This genome is also included in the current web release.

The updated assembly for Acinetobacter sp. RUH2624 was also considered part of this project, but was released as part of the HMP project instead, since it had been originally released under it.

This sequencing project was supported by the National Institute of Allergy and Infectious Disease, National Institutes of Health funded Genome Sequencing Center for Infectious Diseases at the Broad Institute.