Steven A. Carr

Steven A. Carr, Ph.D.

Steven Carr is director of the Proteomics Platform at the Broad Institute of MIT and Harvard. He is internationally recognized as a leader in the development of novel proteomics methods and in their application in biology and medicine.

Carr and his group collaborate with scientists throughout the Broad Institute community (Harvard University, Harvard Medical School, and the 17 Harvard-affiliated hospitals) to apply state-of-the-art proteomics technology to address compelling questions in biology, chemistry, and clinical medicine. Research in his lab focuses on detecting and quantifying post-translational modifications (phosphorylation, acetylation, ubiquitylation, methylation, etc.) in the proteome, developing new technologies to quantify proteins in cells and biofluids with high sensitivity and specificity, improving informatics for peptide and protein assignment using mass spectrometry (MS) data, and integrating MS-derived data with genomic data. The Carr group is also known for developing and applying systematic approaches for biomarker discovery and validation to ultimately provide biomarkers for cancers, heart disease, infectious diseases, and metabolic disorders.

Prior to joining the Broad Institute in 2004, Carr held scientific leadership positions in the pharmaceutical and biotechnology industries, including Director of Computational and Structural Sciences at GlaxoSmithKline Pharmaceuticals and Senior Director of Protein Science and Technology at Millennium Pharmaceuticals in Cambridge, Massachusetts. He has over 200 publications on the development and use of proteomics and biological mass spectrometry. He is also an associate editor of Molecular and Cellular Proteomics, and has served on the editorial boards of Analytical Chemistry and Protein Science, among others.

Carr is the recipient of a number of awards, including the 2011 Discovery Award in Proteomics from the Human Proteome Organization, the 2011 Thought Leader Award in Proteomics from the Agilent Foundation, and the 2014 Wallace H. Coulter Lectureship Award.

Carr received his B.S. from Union College and Ph.D. from MIT.