Supplementary Dataset for Butte et al Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks.

Relevance networks NCI 60 (space separated) dataset

This dataset contain measurements corresponding to baseline RNA expression levels measured from the NCI60, a set of 60 human cancer cell lines used by the National Cancer Institute Developmental Therapeutics Program to screen anticancer agents since 1989. Details about the experimental method and protocol can be found in the "Golub et al" entry in the protocols section. Intensity values have been re-scaled such that overall intensities for each chip are equivalent. This is done by fitting a linear regression model using the intensities of all genes with "P" (present) calls in both the first sample (baseline) and each of the other samples. The inverse of the "slope" of the linear regression line becomes the (multiplicative) re-scaling factor for the current sample. This is done for every chip (sample) in the dataset except the baseline which gets a re-scaling factor of one.