Integrative Genomics Portal (Broad IGP)
 Welcome to the Broad Integrative Genomics Portal, which allows the sharing (both private and public) of annotated and integrated genomic datasets. The portal provides both data analyses and visualizations. To view planned future enhancements you may access the development prototype.
Funding for development of the Integrative Genomics Portal was provided by the Starr Cancer Consortium.
News / Events
May 20, 2013: The server issues have been resolved. Differntial Expression, GSEA and sample browsing are working normally again.
May 20, 2013: Due to a change in some servers the IGP depends on the Differential Expression, GSEA and sample browsing features are currently not working. We are trying to resolve the issue as quickly as possible to bring the portal back to full capability
Dec 7, 2012: IGP Downtime: The IGP may be unavailable all day (EST) on December 15th due to electrical work at the Broad Institute.
Nov 9, 2012: IGP Downtime. The Broad Integrative Genomics Portal will be unavailable on November 13th from 11am to 3pm EST for system maintenance at the Broad Institute.
Nov 7, 2012: New Dataset added: Modeling genomic diversity and tumor dependency in malignant melanoma
Oct 15, 2012: New feature: deep links to gene pages. You can now link directly to gene pages from other applications and portals using urls that include the gene symbol like this http://www.broadinstitute.org/IGP/gene/FGFR3
Oct 12, 2012: New Feature: you can now download the RNAi data used to generate the heat map on the gene pages.
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New User?
Please register for full access to the data and analyses tools Broad IGP provides.
Terms of Access Register
Tutorials / Manuals
Tutorials, analysis descriptions and other documentation is available at:
HELP > DOCUMENTS
Frequently Altered Genes
Tag
clouds summarizing genes frequently altered in the datasets of this
portal are available in the
Mutation tag cloud
Publications
 ATARiS: Computational quantification of gene suppression phenotypes from multi-sample RNAi screens., Shao DD et al., Genome Research, 2012
Modeling Genomic Diversity and Tumor Dependency in Malignant Melanoma, William M. Lin et al, Cancer Research, 2007
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer, Hiu Wing Cheung et al., PNAS, 2011
All Publications |
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What you can do on this portal
Search for information
Enter a keyword to search for genes, news items and publications. Search
results for a gene include links to annotations and analyses.
Data Sets
 Browse, analyze and download
studies and data sets.
BROWSE > DATA
Analysis Tools
 The portal provides the
following analysis tools:
Integrative Genomics Viewer (IGV)
Visualize a data set in the Integrative Genomics Viewer (IGV), a high-performance
visualization tool for interactive exploration of large integrated data sets.
Differential Expression Analysis
Find genes that are significantly differentially expressed between two user-defined classes
of samples from an expression data set available on this portal.
Gene co-expression
View the top 20 genes in a data set that are co-expressed with a gene of interest.
Gene Set Enrichment Analysis (GSEA)
Find pathway gene sets correlated with a gene of interest. Domain
experts curate the pathway gene sets based on data from several online pathway databases.
ANALYSIS TOOLS
Sample Sets
 Create your own sample sets based on a
large number of available criteria and use them in differential expression analysis.
CREATE SAMPLE SETS
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