Integrative Genomics Portal (Broad IGP)
 Welcome to the Broad Integrative Genomics Portal, which allows the sharing (both private and public) of annotated and integrated genomic datasets. The portal provides both data analyses and visualizations. To view planned future enhancements you may access the development prototype.
Funding for development of the Integrative Genomics Portal was provided by the Starr Cancer Consortium.
News / Events
Mar 20, 2012: The portal has been updated to 2.13.10 and the GENE-E application to version 2.0.13
Nov 21, 2011: The IGP Portal will be unavailable Tues Nov 22, 2011 from 11-3pm for scheduled maintenance on the underlying servers.
Mar 29, 2011: The portal has been updated to version 2.11.7
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New User?
Please register for full access to the data and analyses tools Broad IGP provides.
Terms of Access Register
Tutorials / Manuals
Tutorials, analysis descriptions and other documentation is available at:
HELP > DOCUMENTS
Frequently Altered Genes
Tag clouds summarizing genes frequently altered in the datasets of this portal are available in the
Mutation tag cloud
Publications
 Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer, Hiu Wing Cheung et al., PNAS, 2011
RNA interference reveals that oncogenic KRAS-driven cancers , David A. Barbie et al., Nature, 2010
All Publications
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What you can do on this portal
Search for information
Enter a keyword to search for genes, news items and publications. Search
results for a gene include links to annotations and analyses.
Data Sets
 Browse, analyze and download studies and data sets.
BROWSE > DATA
Analysis Tools
 The portal provides the following analysis tools:
Integrative Genomics Viewer (IGV)
Visualize a data set in the Integrative Genomics Viewer (IGV), a high-performance visualization tool for interactive exploration of
large integrated data sets.
Differential Expression Analysis
Find genes that are significantly differentially expressed between two user-defined
classes of samples from an expression data set available on this portal.
Gene co-expression
View the top 20 genes in a data set that are co-expressed with a gene of interest.
Gene Set Enrichment Analysis (GSEA)
Find pathway gene sets correlated with a gene of interest. Domain experts curate the pathway
gene sets based on data from several online pathway databases.
ANALYSIS TOOLS
Sample Sets
Create your own sample sets based on a large number of available criteria and use them in differential expression analysis.
CREATE SAMPLE SETS
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