Integrative Genomics Portal (Broad IGP)

Welcome to the Broad Integrative Genomics Portal, which allows the sharing (both private and public) of annotated and integrated genomic datasets. The portal provides both data analyses and visualizations. To view planned future enhancements you may access the development prototype.


Funding for development of the Integrative Genomics Portal was provided by the Starr Cancer Consortium.


News / Events

Jun 3, 2014: The portal will be unavailable Friday June 6th from 10 AM through 1 PM EST for maintenance. 

Sep 18, 2013: The portal will be unavailable from Thursday October 17 through Sunday October 20th for server maintenance. 

Sep 3, 2013: The Project Achilles now has its own portal available at http://www.broadinstitute.org/achilles. All future updates of Project Achilles will be distributed there.  more...

May 20, 2013: The server issues have been resolved. Differntial Expression, GSEA and sample browsing are working normally again. 

May 20, 2013: Due to a change in some servers the IGP depends on the Differential Expression, GSEA and sample browsing features are currently not working. We are trying to resolve the issue as quickly as possible to bring the portal back to full capability 

Dec 7, 2012: IGP Downtime: The IGP may be unavailable all day (EST) on December 15th due to electrical work at the Broad Institute. 

Nov 9, 2012: IGP Downtime. The Broad Integrative Genomics Portal will be unavailable on November 13th from 11am to 3pm EST for system maintenance at the Broad Institute. 

New User?

Please register for full access to the data and analyses tools Broad IGP provides.


Terms of Access   Register

Tutorials / Manuals

Tutorials, analysis descriptions and other documentation is available at:
HELP > DOCUMENTS

Frequently Altered Genes

Tag clouds summarizing genes frequently altered in the datasets of this portal are available in the
Mutation tag cloud

Publications

ATARiS: Computational quantification of gene suppression phenotypes from multi-sample RNAi screens.,  Shao DD et al., Genome Research, 2012

Modeling Genomic Diversity and Tumor Dependency in Malignant Melanoma,  William M. Lin et al, Cancer Research, 2007

Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer,  Hiu Wing Cheung et al., PNAS, 2011

All Publications

What you can do on this portal

Search for information

Enter a keyword to search for genes, news items and publications. Search results for a gene include links to annotations and analyses.

Data Sets

Browse, analyze and download studies and data sets.

BROWSE   > DATA

Analysis Tools

The portal provides the following analysis tools:

Integrative Genomics Viewer (IGV)
Visualize a data set in the Integrative Genomics Viewer (IGV), a high-performance visualization tool for interactive exploration of large integrated data sets.

Differential Expression Analysis
Find genes that are significantly differentially expressed between two user-defined classes of samples from an expression data set available on this portal.

Gene co-expression
View the top 20 genes in a data set that are co-expressed with a gene of interest.

Gene Set Enrichment Analysis (GSEA)
Find pathway gene sets correlated with a gene of interest. Domain experts curate the pathway gene sets based on data from several online pathway databases.

ANALYSIS TOOLS

Sample Sets

Create your own sample sets based on a large number of available criteria and use them in differential expression analysis.
CREATE SAMPLE SETS