Integrative Genomics Portal (Broad IGP)
Welcome to the Broad Integrative Genomics Portal, which allows the sharing (both private and public) of annotated and integrated genomic datasets. The portal provides both data analyses and visualizations. To view planned future enhancements you may access the development prototype.
Funding for development of the Integrative Genomics Portal was provided by the Starr Cancer Consortium.
News / Events
Jun 8, 2015: The IGP portal will be unavailable Sunday June 14th 12 noon through Monday June 15th, 12 noon for maintenance.
Mar 11, 2015: The IGP portal will be unavailable on Tuesday 3/24/2015 for scheduled maintenance.
Jun 3, 2014: The portal will be unavailable Friday June 6th from 10 AM through 1 PM EST for maintenance.
Sep 18, 2013: The portal will be unavailable from Thursday October 17 through Sunday October 20th for server maintenance.
Sep 3, 2013: The Project Achilles now has its own portal available at http://www.broadinstitute.org/achilles. All future updates of Project Achilles will be distributed there.
May 20, 2013: The server issues have been resolved. Differntial Expression, GSEA and sample browsing are working normally again.
May 20, 2013: Due to a change in some servers the IGP depends on the Differential Expression, GSEA and sample browsing features are currently not working. We are trying to resolve the issue as quickly as possible to bring the portal back to full capability
Please register for full access to the data and analyses tools Broad IGP provides.
Terms of Access Register
Tutorials / Manuals
Tutorials, analysis descriptions and other documentation is available at:
HELP > DOCUMENTS
Frequently Altered Genes
clouds summarizing genes frequently altered in the datasets of this
portal are available in the
Mutation tag cloud
ATARiS: Computational quantification of gene suppression phenotypes from multi-sample RNAi screens., Shao DD et al., Genome Research, 2012
Modeling Genomic Diversity and Tumor Dependency in Malignant Melanoma, William M. Lin et al, Cancer Research, 2007
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer, Hiu Wing Cheung et al., PNAS, 2011
What you can do on this portal
Search for information
Enter a keyword to search for genes, news items and publications. Search
results for a gene include links to annotations and analyses.
Browse, analyze and download
studies and data sets.
BROWSE > DATA
The portal provides the
following analysis tools:
Integrative Genomics Viewer (IGV)
Visualize a data set in the Integrative Genomics Viewer (IGV), a high-performance
visualization tool for interactive exploration of large integrated data sets.
Differential Expression Analysis
Find genes that are significantly differentially expressed between two user-defined classes
of samples from an expression data set available on this portal.
View the top 20 genes in a data set that are co-expressed with a gene of interest.
Gene Set Enrichment Analysis (GSEA)
Find pathway gene sets correlated with a gene of interest. Domain
experts curate the pathway gene sets based on data from several online pathway databases.
Create your own sample sets based on a
large number of available criteria and use them in differential expression analysis.
CREATE SAMPLE SETS